# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4007073 | A | Cytotoxicity against human HeLa cells assessed as changes in morphology after 3 days by microscopic method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
2. | ALA4007074 | A | Cytotoxicity against human HeLa cells assessed as reduction in cell viability by XTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
3. | ALA4007075 | F | Antiviral activity against HRV 1B infected in human HeLa cells after 72 hrs by plaque reduction assay | Human rhinovirus 1B | 16 | cell-based format | Scientific Literature | ||
4. | ALA4007076 | U | Selectivity index, ratio of CC50 for human HeLa cells to IC50 for HRV 1B infected in human HeLa cells | 13 | cell-based format | Scientific Literature | |||
5. | ALA4007077 | F | Antiviral activity against HRV 14 infected in human HeLa cells after 72 hrs by plaque reduction assay | rhinovirus B14 | 15 | cell-based format | Scientific Literature | ||
6. | ALA4007078 | U | Selectivity index, ratio of CC50 for human HeLa cells to IC50 for HRV 14 infected in human HeLa cells | 6 | cell-based format | Scientific Literature | |||
7. | ALA4007079 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM pretreated with cells for 1 hr followed by viral infection at 4 degC measured after 10 hrs by plaque reduction assay relative to control | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
8. | ALA4007080 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM treated for 1 hr during virus adsorption at 4 degC measured after 10 hrs by plaque reduction assay | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
9. | ALA4007081 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM treated during viral binding and multiplication at 4 degC measured after 10 hrs by plaque reduction assay relative to control | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
10. | ALA4007082 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM treated immediately after viral adsorption followed by removal of compound at 0.25 to 1 hr post infection measured after 10 hrs incubation at 33 degC by plaque reduction assay relative to control | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
11. | ALA4007083 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM treated immediately after viral adsorption followed by removal of compound at 2 to 6 hrs post infection measured after 10 hrs incubation at 33 degC by plaque reduction assay | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
12. | ALA4007084 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as viral titre level at 48.5 uM after 1 hr at 33 degC (Rvb = 1.63 10'7PFU/ml) | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
13. | ALA4007085 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM treated 30 mins after viral adsorption at 4 degC measured after 10 hrs by plaque reduction assay relative to control | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
14. | ALA4007088 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM treated immediately after viral adsorption at 4 degC measured after 10 hrs by plaque reduction assay relative to control | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
15. | ALA4007089 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM treated 1 hr after viral adsorption at 4 degC measured after 10 hrs by plaque reduction assay relative to control | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
16. | ALA4007090 | F | Antiviral activity against HRV 1B infected in human HeLa cells assessed as reduction in viral yield at 48.5 uM treated 2 to 4 hrs after viral adsorption at 4 degC measured after 10 hrs by plaque reduction assay | Human rhinovirus 1B | 1 | cell-based format | Scientific Literature | ||
17. | ALA4007091 | B | Binding affinity to capsid in HRV 1B assessed as protection against acid inactivation of viral infectivity by measuring reduction in viral infection at 48.5 uM pretreated for 1 hr at 33 degC followed by mild acid treatment at pH 5 for 30 mins by plaque reduction assay (Rvb = 3.1 No_unit) | Human rhinovirus 1B | 1 | assay format | Scientific Literature | ||
18. | ALA4007092 | B | Binding affinity to capsid in HRV 1B assessed as protection against acid inactivation of viral infectivity by measuring reduction in viral infection at 48.5 uM pretreated for 1 hr at 33 degC followed by thermal inactivation at 56 degC for 20 mins by plaque reduction assay (Rvb = 5.4 No_unit) | Human rhinovirus 1B | 1 | assay format | Scientific Literature |