# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3992745 | B | Inhibition of GLUT1 in human A431 cells assessed as reduction in 2-[1,2-3H]deoxy-D-glucose uptake measured after 30 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA3992488 | cell-based format | Scientific Literature | |
2. | ALA4312907 | F | Cytotoxicity against human ACHN cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 22 | ALA4311948 | cell-based format | Scientific Literature | |
3. | ALA4312908 | F | Cytotoxicity against human OS-RC2 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 22 | ALA4311948 | cell-based format | Scientific Literature | |
4. | ALA4312909 | F | Cytotoxicity against human 786-O cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 22 | ALA4311948 | cell-based format | Scientific Literature | |
5. | ALA4312910 | A | Cytotoxicity against human HK2 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 22 | ALA4311948 | cell-based format | Scientific Literature | |
6. | ALA4312911 | F | Cytotoxicity against human ACHN cells harboring shPRDX1 gene assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 22 | ALA4311948 | cell-based format | Scientific Literature | |
7. | ALA4312912 | F | Down regulation of EGFR mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
8. | ALA4312913 | F | Down regulation of SOD2 mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
9. | ALA4312914 | F | Down regulation of ETS1 mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
10. | ALA4312915 | F | Down regulation of HK2 mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
11. | ALA4312916 | F | Down regulation of SLC2A1 mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
12. | ALA4312917 | F | Down regulation of LDHA mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
13. | ALA4312918 | F | Down regulation of MET mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
14. | ALA4312919 | F | Down regulation of HIF1A mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
15. | ALA4312920 | F | Up regulation of PRDX1 mRNA expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
16. | ALA4312921 | B | Activation of PRDX1 in human ACHN cells assessed as reduction in reactive oxygen species level at 25 to 50 nM measured after 24 hrs by Cell-rox reagent-based flow cytometry | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
17. | ALA4312922 | F | Antioxidant activity in human ACHN cells harboring shPRDX1 gene assessed as reduction in reactive oxygen species level at 25 to 50 nM measured after 24 hrs by Cell-rox reagent-based flow cytometry | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
18. | ALA4312932 | F | Selectivity ratio of IC50 for cytotoxicity against human ACHN cells harboring shPRDX1 gene to IC50 for Cytotoxicity against human ACHN cells | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
19. | ALA4312933 | F | Up regulation of nuclear PRDX1 expression in human ACHN cells at 25 to 50 nM measured after 24 hrs by immunoblot analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature | |
20. | ALA4312934 | B | Induction of PRDX1 nuclear translocation in human ACHN cells at 25 to 50 nM measured after 24 hrs by DAPI staining-based microscopic analysis | Homo sapiens | 2 | ALA4311948 | cell-based format | Scientific Literature |