| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4043777 | B | Inhibition of human recombinant His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-based Z'-Lyte assay | Homo sapiens | 23 | ALA4043093 | assay format | Scientific Literature | |
| 2. | ALA4043778 | B | Inhibition of human recombinant cytoplasmic His-tagged FGFR2 (403 to 822 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-based Z'-Lyte assay | Homo sapiens | 14 | ALA4043093 | assay format | Scientific Literature | |
| 3. | ALA4043779 | B | Inhibition of human recombinant His-tagged FGFR3 cytoplasmic domain (399 to 806 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-based Z'-Lyte assay | Homo sapiens | 14 | ALA4043093 | assay format | Scientific Literature | |
| 4. | ALA4043780 | B | Inhibition of human recombinant His-tagged FGFR4 cytoplasmic domain (781 to 1338 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-based Z'-Lyte assay | Homo sapiens | 14 | ALA4043093 | assay format | Scientific Literature | |
| 5. | ALA4043781 | F | Antiproliferative activity against human FGFR1-amplified NCI-H520 cells after 7 days by SRB assay | Homo sapiens | 15 | ALA4043093 | cell-based format | Scientific Literature | |
| 6. | ALA4043782 | F | Antiproliferative activity against human FGFR3-amplified SW780 cells after 5 days by SRB assay | Homo sapiens | 15 | ALA4043093 | cell-based format | Scientific Literature | |
| 7. | ALA4043792 | F | Antiproliferative activity against human FGFR2-amplified SUM52 cells after 5 days by SRB assay | Homo sapiens | 15 | ALA4043093 | cell-based format | Scientific Literature | |
| 8. | ALA4043793 | B | Inhibition of human wild-type AAK1 (G25 to L333 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | assay format | Scientific Literature | |
| 9. | ALA4043794 | B | Inhibition of human phosphorylated ABL1 E255K mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 10. | ALA4043795 | B | Inhibition of human non-phosphorylated ABL1 F317I mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 11. | ALA4043796 | B | Inhibition of human phosphorylated ABL1 F317I mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 12. | ALA4043797 | B | Inhibition of human non-phosphorylated ABL1 F317L mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 13. | ALA4043798 | B | Inhibition of human phosphorylated ABL1 F317L mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 14. | ALA4043799 | B | Inhibition of human non-phosphorylated ABL1 H396P mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 15. | ALA4043800 | B | Inhibition of human phosphorylated ABL1 H396P mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 16. | ALA4043801 | B | Inhibition of human phosphorylated ABL1 M351T mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 17. | ALA4043802 | B | Inhibition of human non-phosphorylated ABL1 Q252H mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 18. | ALA4043803 | B | Inhibition of human phosphorylated ABL1 Q252H mutant expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 19. | ALA4043804 | B | Inhibition of human non-phosphorylated ABL1 T315I mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
| 20. | ALA4043805 | B | Inhibition of human phosphorylated ABL1 T315I mutant (S229 to K512 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature |
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