# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3995154 | Binding | Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence of NADH by RP-HPLC method | Homo sapiens | 32 | ALA3994586 | assay format | Scientific Literature | |
2. | ALA3995155 | Binding | Inhibition of human placental microsomal 17beta-HSD2 using [2,4,6,7-3H]-E2 as substrate after 20 mins in presence of NAD+ by RP-HPLC method | Homo sapiens | 32 | ALA3994586 | assay format | Scientific Literature | |
3. | ALA3995156 | Binding | Selectivity ratio of IC50 for human placental microsomal 17beta-HSD2 to IC50 for human placental cytosolic 17beta-HSD1 | Homo sapiens | 32 | ALA3994586 | assay format | Scientific Literature | |
4. | ALA4261346 | Binding | Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate after 20 mins in presence of NAD+ by radio-flow detector based analysis | Homo sapiens | 36 | ALA4257592 | assay format | Scientific Literature | |
5. | ALA4261347 | Binding | Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analysis | Homo sapiens | 36 | ALA4257592 | assay format | Scientific Literature | |
6. | ALA4261350 | Binding | Selectivity ratio of human placental cytosolic 17beta-HSD1 to IC50 for human placental microsomal fraction 17beta-HSD2 | Homo sapiens | 36 | ALA4257592 | assay format | Scientific Literature | |
7. | ALA4261352 | Binding | Inhibition of mouse microsomal fraction 17beta-HSD2 at 250 nM using [3H]-E2 as substrate after 20 mins in presence of NAD+ by radio-flow detector based analysis relative to control | Mus musculus | 1 | ALA4257592 | assay format | Scientific Literature | |
8. | ALA4261354 | Binding | Inhibition of recombinant mouse 17beta-HSD1 at 1000 nM using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analysis relative to control | Mus musculus | 36 | ALA4257592 | single protein format | Scientific Literature |