| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4044621 | B | Inhibition of recombinant full length human DGAT1 expressed in Sf9 insect cells using 1,2-didecanoyl-sn-glycerol as substrate at 1 uM after 60 mins in presence of palmitoyl-1-14C coenzyme A by scintillation counting | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 2. | ALA4044622 | B | Inhibition of recombinant full length human DGAT1 expressed in Sf9 insect cells using 1,2-didecanoyl-sn-glycerol as substrate at 0.1 uM after 60 mins in presence of palmitoyl-1-14C coenzyme A by scintillation counting | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 3. | ALA4044623 | B | Inhibition of recombinant full length human DGAT1 expressed in Sf9 insect cells using 1,2-didecanoyl-sn-glycerol as substrate after 60 mins in presence of palmitoyl-1-14C coenzyme A by scintillation counting | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 4. | ALA4044624 | P | Solubility of the compound in HBSS/HEPES/BSA buffer of pH 6.8 by nephelometry | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA4044625 | P | Solubility of the compound in HBSS/HEPES/BSA buffer of pH 7.4 by nephelometry | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4044626 | A | Apparent permeability of the compound across apical side to basolateral side in human Caco2 cells after 95 mins by LC-MS/MS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4044627 | A | Apparent permeability of the compound across basolateral side to apical side in human Caco2 cells after 95 mins by LC-MS/MS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4044628 | A | Efflux ratio of permeability from apical to basolateral side over basolateral to apical side in human Caco2 cells after 95 mins by LC-MS/MS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4044629 | A | AUC (0 to infinity) in ig dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4044630 | A | AUC (0 to infinity) in iv dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4044631 | A | MRT in ig dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4044632 | A | MRT in iv dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4044633 | A | Elimination half life in ig dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4044634 | A | Elimination half life in iv dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4044635 | A | Tmax in ig dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4044636 | A | Cmax in ig dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4044637 | A | Clearance in iv dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4044638 | A | Volume of distribution at steady state in iv dosed Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4044639 | A | Oral bioavailability in Sprague-Dawley rat by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4044640 | A | Plasma concentration in C57 mouse at 10 mg/kg, po after 1 hr by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature |
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