| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4015578 | A | Cytotoxicity against human HuH7 cells after 3 days by CellTiter-Blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4015579 | B | Inhibition of HCV genotype 1b NS5B replicase C316N mutant infected in human HuH7 cells assessed as reduction of viral replication after 3 days by luciferase reporter assay | Hepatitis C virus subtype 1b | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA4015581 | F | Antiviral activity against HCV genotype 1b infected in human HuH7 cells after 3 days by luciferase reporter assay | Hepacivirus hominis | 28 | cell-based format | Scientific Literature | ||
| 4. | ALA4015582 | F | Antiviral activity against HCV genotype 1a infected in human HuH7 cells after 3 days by luciferase reporter assay | Hepacivirus hominis | 28 | cell-based format | Scientific Literature | ||
| 5. | ALA4015586 | A | Half life in human liver microsomes | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 6. | ALA4015587 | A | Half life in rat liver microsomes | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
| 7. | ALA4015588 | P | Membrane permeability at pH 7.4 by PAMPA | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA4015590 | A | Drug uptake in Sprague-Dawley rat liver at 6 mg/kg, po via gavage after 6 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA4015592 | A | Inhibition of microsomal CYP2C8 (unknown origin) | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 10. | ALA4015593 | A | Inhibition of microsomal CYP3A4 (unknown origin) | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 11. | ALA4015594 | A | Half life in dog liver microsomes | Canis lupus familiaris | 3 | assay format | Scientific Literature | ||
| 12. | ALA4015595 | A | Half life in monkey liver microsomes | Macaca mulatta | 4 | assay format | Scientific Literature | ||
| 13. | ALA4015596 | B | Inhibition of human ERG by thallium flux assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA4015597 | A | Transactivation of PXR (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA4015598 | U | Ratio of plasma concentration in human at 25 mg/day administered as single dose to EC50 for HCV genotype 1b NS5B C316N mutant infected in human HuH7 cells | 1 | cell-based format | Scientific Literature | |||
| 16. | ALA4015599 | U | Ratio of plasma concentration in human at 25 mg up to 14 days to EC50 for HCV genotype 1b NS5B C316N mutant infected in human HuH7 cells | 1 | cell-based format | Scientific Literature | |||
| 17. | ALA4015600 | T | Toxicity in dog up to 100 mg/kg, po administered as single dose measured up to 2 weeks | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4015601 | P | Lipophilicity, log D of the compound at pH 6.5 by shake flask method | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 19. | ALA4015602 | B | Inhibition of human ERG at 10 uM by patch clamp assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 20. | ALA4015603 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv by LC/MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature |
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