# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4031608 | B | Substrate activity at PTS in CHO cells assessed as reduction in cell viability after 48 hrs in presence of aminoguanidine by MTS assay | Cricetulus griseus | 8 | ALA4028869 | cell-based format | Scientific Literature | |
2. | ALA4031609 | A | Cytotoxicity against CHO-MG cells assessed as reduction in cell viability after 48 hrs in presence of aminoguanidine by MTS assay | Cricetulus griseus | 8 | ALA4028869 | cell-based format | Scientific Literature | |
3. | ALA4031610 | U | Selectivity ratio of IC50 for CHO-MG cells to IC50 for PTS in CHO cells | Cricetulus griseus | 10 | ALA4028869 | cell-based format | Scientific Literature | |
4. | ALA4031611 | F | Antiproliferative activity against human L3.6p1 cells after 48 hrs in presence of amine oxidase inhibitor aminoguanidine by MTS assay | Homo sapiens | 8 | ALA4028869 | cell-based format | Scientific Literature | |
5. | ALA4031612 | F | Antimigratory activity against human L3.6p1 cells at 0.5 uM after 24 hrs in presence of amine oxidase inhibitor aminoguanidine by scratch assay relative to control | Homo sapiens | 7 | ALA4028869 | cell-based format | Scientific Literature | |
6. | ALA4031613 | F | Antimigratory activity against human L3.6p1 cells at 1 uM after 24 hrs in presence of amine oxidase inhibitor aminoguanidine by scratch assay relative to control | Homo sapiens | 10 | ALA4028869 | cell-based format | Scientific Literature | |
7. | ALA4031614 | F | Modulation of ceramide pool in human L3.6p1 cells assessed as N16:0 level per mg protein at 500 nM after 48 hrs (Rvb = 0.08 +/- 0.01 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
8. | ALA4031615 | F | Modulation of ceramide pool in human L3.6p1 cells assessed as N24:1 level per mg protein at 500 nM after 48 hrs (Rvb = 0.37 +/- 0.06 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
9. | ALA4031616 | F | Modulation of ceramide pool in human L3.6p1 cells assessed as N24:0 level per mg protein at 500 nM after 48 hrs (Rvb = 0.16 +/- 0.04 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
10. | ALA4031617 | F | Modulation of ceramide pool in human L3.6p1 cells assessed as total ceramide level per mg protein at 500 nM after 48 hrs (Rvb = 0.62 +/- 0.10 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
11. | ALA4031618 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N14:0 level per mg protein at 500 nM after 48 hrs (Rvb = 0.13 +/- 0.01 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
12. | ALA4031619 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N15:0 level per mg protein at 500 nM after 48 hrs (Rvb = 0.12 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
13. | ALA4031620 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N16:1 level per mg protein at 500 nM after 48 hrs (Rvb = 0.28 +/- 0.01 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
14. | ALA4031621 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N16:0 level per mg protein at 500 nM after 48 hrs (Rvb = 2.60 +/- 0.06 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
15. | ALA4031622 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N17:0 level per mg protein at 500 nM after 48 hrs (Rvb = 0.05 +/- 0.01 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
16. | ALA4031623 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N18:1 level per mg protein at 500 nM after 48 hrs (Rvb = 0.07 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
17. | ALA4031624 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N18:0 level per mg protein at 500 nM after 48 hrs (Rvb = 0.19 +/- 0.01 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
18. | ALA4031625 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N19:0 level per mg protein at 500 nM after 48 hrs (Rvb = 0.01 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
19. | ALA4031626 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N20:1 level per mg protein at 500 nM after 48 hrs (Rvb = 0.02 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature | |
20. | ALA4031627 | F | Modulation of sphingomyelin pool in human L3.6p1 cells assessed as N20:0 level per mg protein at 500 nM after 48 hrs (Rvb = 0.06 +/- 0.01 nmol) | Homo sapiens | 3 | ALA4028869 | cell-based format | Scientific Literature |