# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4005390 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability up to 100 ug/ml after 24 hrs by MTT assay | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
2. | ALA4005391 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced TNFalpha production preincubated for 2 hrs followed by LPS stimulation for 24 hrs by ELISA | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
3. | ALA4005392 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-6 production preincubated for 2 hrs followed by LPS stimulation for 24 hrs by ELISA | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
4. | ALA4005393 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NO production up to 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess assay | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
5. | ALA4005394 | B | Inhibition of NF-kB (unknown origin) activation expressed in LPS-stimulated mouse RAW264.7 cells up to 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 4 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4004813 | cell-based format | Scientific Literature | |
6. | ALA4005395 | B | Inhibition of p65 nuclear translocation in LPS-stimulated mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 4 hrs by Western blot method | Mus musculus | 1 | ALA4004813 | assay format | Scientific Literature | |
7. | ALA4005396 | B | Inhibition of LPS-induced degradation of IkappaB-alpha in mouse RAW264.7 cells at 10 ug/ml preincubated for 2 hrs followed by LPS stimulation up to 45 mins by Western blot method | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
8. | ALA4005397 | B | Inhibition of AP-1 (unknown origin) activation expressed in LPS-stimulated mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 4 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4004813 | cell-based format | Scientific Literature | |
9. | ALA4005398 | B | Inhibition of LPS-induced nuclear translocation of AP-1 c-Jun component in mouse RAW264.7 cells up to 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 4 hrs by Western blot method | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
10. | ALA4005399 | B | Inhibition of LPS-induced nuclear translocation of AP-1 c-Fos component in mouse RAW264.7 cells up to 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 4 hrs by Western blot method | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
11. | ALA4005400 | F | Induction of LPS-induced ATF-3 expression in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 4 hrs by Western blot method | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
12. | ALA4005401 | F | Anti-inflammatory activity in mouse RAW264.7 cells transfected with ATF-3 shRNA assessed as reduction in LPS-induced TNFalpha production at 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 24 hrs by ELISA | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
13. | ALA4005402 | F | Anti-inflammatory activity in mouse RAW264.7 cells transfected with ATF-3 shRNA assessed as reduction in LPS-induced IL-6 production at 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 24 hrs by ELISA | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
14. | ALA4005403 | B | Inhibition of LPS-induced JNK phosphorylation in mouse RAW264.7 cells up to 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 15 mins by Western blot method | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
15. | ALA4005404 | B | Inhibition of LPS-induced ERK1/2 phosphorylation in mouse RAW264.7 cells up to 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 15 mins by Western blot method | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature | |
16. | ALA4005405 | B | Inhibition of LPS-induced MAPK p38 phosphorylation in mouse RAW264.7 cells up to 10 ug/ml preincubated for 2 hrs followed by LPS stimulation for 15 mins by Western blot method | Mus musculus | 1 | ALA4004813 | cell-based format | Scientific Literature |