# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4052329 | Binding | Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by substrate addition measured every 2 mins for 1 hr by amplex red reagent-based fluorescence assay | Homo sapiens | 30 | ALA4049456 | cell-based format | Scientific Literature | |
2. | ALA4052332 | Binding | Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by substrate addition in presence of 0.1% BSA measured every 2 mins for 1 hr by amplex red reagent-based fluorescence assay | Homo sapiens | 30 | ALA4049456 | cell-based format | Scientific Literature | |
3. | ALA4052333 | Binding | Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by substrate addition in presence of 0.1% BSA measured every 2 mins for 1 hr by amplex red reagent-based fluorescence assay | Homo sapiens | 30 | ALA4049456 | cell-based format | Scientific Literature | |
4. | ALA4052334 | Binding | Inhibition of recombinant human LOXL2 expressed in human whole blood assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by substrate addition measured every 2 mins for 1 hr by amplex red reagent-based fluorescence assay | Homo sapiens | 30 | ALA4049456 | assay format | Scientific Literature | |
5. | ALA4052342 | Binding | Selectivity ratio of IC50 for human LOX expressed in HEK cells in presence of 0.1% BSA to IC50 for human LOXL2 expressed in CHO cells in presence of 0.1% BSA | Homo sapiens | 6 | ALA4049456 | cell-based format | Scientific Literature |