# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4019211 | Binding | Inhibition of AEP (unknown origin) assessed as residual activity at 1 uM using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assay relative to control | Homo sapiens | 26 | ALA4017504 | single protein format | Scientific Literature | |
2. | ALA4019212 | Binding | Inhibition of cathepsin-L (unknown origin) | Homo sapiens | 4 | ALA4017504 | assay format | Scientific Literature | |
3. | ALA4019213 | Binding | Inhibition of AEP (unknown origin) using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assay | Homo sapiens | 4 | ALA4017504 | single protein format | Scientific Literature | |
4. | ALA4019214 | Binding | Inhibition of cathepsin-S (unknown origin) | Homo sapiens | 4 | ALA4017504 | single protein format | Scientific Literature | |
5. | ALA4019215 | Binding | Inhibition of caspase-3 (unknown origin) | Homo sapiens | 4 | ALA4017504 | single protein format | Scientific Literature | |
6. | ALA4019216 | Binding | Inhibition of caspase-8 (unknown origin) | Homo sapiens | 4 | ALA4017504 | single protein format | Scientific Literature | |
7. | ALA4019217 | Binding | Selectivity ratio of IC50 for cathepsin-L (unknown origin) to IC50 for AEP (unknown origin) | Homo sapiens | 2 | ALA4017504 | assay format | Scientific Literature | |
8. | ALA4019218 | ADME | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability up to 2 uM by MTT assay | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
9. | ALA4019219 | ADME | Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell viability up to 2 uM by MTT assay | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
10. | ALA4019220 | Functional | Anti-invasive activity against human MDA-MB-231 cells by crystal violet staining based microscopic method | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
11. | ALA4019221 | Functional | Anti-invasive activity against human MDA-MB-435 cells by crystal violet staining based microscopic method | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
12. | ALA4019222 | Functional | Anti-invasive activity against human MDA-MB-231 cells at 2 uM by crystal violet staining based microscopic method relative to control | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
13. | ALA4019223 | Functional | Anti-invasive activity against human MDA-MB-435 cells at 2 uM by crystal violet staining based microscopic method relative to control | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
14. | ALA4019224 | Functional | Anti-migratory activity against human MDA-MB-231 cells up to 2 uM by transwell assay relative to control | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
15. | ALA4019225 | Functional | Anti-migratory activity against human MDA-MB-435 cells up to 2 uM by transwell assay relative to control | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
16. | ALA4019226 | Binding | Inhibition of AEP in human MDA-MB-231 cells | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
17. | ALA4019227 | Binding | Inhibition of AEP in human MDA-MB-435 cells | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
18. | ALA4019228 | Functional | Anti-invasive activity against human MDA-MB-435 cells harboring AEP siRNA up to 2 uM by crystal violet staining based microscopic method | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
19. | ALA4019229 | Functional | Anti-invasive activity against human MDA-MB-231 cells harboring AEP siRNA up to 2 uM by crystal violet staining based microscopic method | Homo sapiens | 1 | ALA4017504 | cell-based format | Scientific Literature | |
20. | ALA4019230 | Functional | Antitumor activity against human MDA-MB-231 cells xenografted in nude mouse assessed as metastatic nodules on lungs at 3 mg/kg, po via gavage for 42 consecutive days by hematoxylin and eosin staining based microscopic method relative to control | Homo sapiens | 1 | ALA4017504 | organism-based format | Scientific Literature |