| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4019211 | B | Inhibition of AEP (unknown origin) assessed as residual activity at 1 uM using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assay relative to control | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 2. | ALA4019212 | B | Inhibition of cathepsin-L (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 3. | ALA4019213 | B | Inhibition of AEP (unknown origin) using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA4019214 | B | Inhibition of cathepsin-S (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA4019215 | B | Inhibition of caspase-3 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 6. | ALA4019216 | B | Inhibition of caspase-8 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 7. | ALA4019217 | B | Selectivity ratio of IC50 for cathepsin-L (unknown origin) to IC50 for AEP (unknown origin) | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 8. | ALA4019218 | A | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability up to 2 uM by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4019219 | A | Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell viability up to 2 uM by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4019220 | F | Anti-invasive activity against human MDA-MB-231 cells by crystal violet staining based microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4019221 | F | Anti-invasive activity against human MDA-MB-435 cells by crystal violet staining based microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4019222 | F | Anti-invasive activity against human MDA-MB-231 cells at 2 uM by crystal violet staining based microscopic method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4019223 | F | Anti-invasive activity against human MDA-MB-435 cells at 2 uM by crystal violet staining based microscopic method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4019224 | F | Anti-migratory activity against human MDA-MB-231 cells up to 2 uM by transwell assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4019225 | F | Anti-migratory activity against human MDA-MB-435 cells up to 2 uM by transwell assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4019226 | B | Inhibition of AEP in human MDA-MB-231 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4019227 | B | Inhibition of AEP in human MDA-MB-435 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4019228 | F | Anti-invasive activity against human MDA-MB-435 cells harboring AEP siRNA up to 2 uM by crystal violet staining based microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4019229 | F | Anti-invasive activity against human MDA-MB-231 cells harboring AEP siRNA up to 2 uM by crystal violet staining based microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4019230 | F | Antitumor activity against human MDA-MB-231 cells xenografted in nude mouse assessed as metastatic nodules on lungs at 3 mg/kg, po via gavage for 42 consecutive days by hematoxylin and eosin staining based microscopic method relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature |
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