# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4016657 | F | Agonist activity at human NMUR2 expressed in CHO cells assessed as induction of Ca2+ flux at 10 nM after 18 hrs by Fluo-4 AM dye based FLIPR assay relative to NMU | Homo sapiens | 10 | ALA4014341 | cell-based format | Scientific Literature | |
2. | ALA4016659 | F | Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux at 0.1 nM after 18 hrs by Fluo-4 AM dye based FLIPR assay relative to NMU | Homo sapiens | 4 | ALA4014341 | cell-based format | Scientific Literature | |
3. | ALA4727275 | A | Stability of the compound in 25% human serum assessed as residual rate at 50 uM incubated for 10 mins at 37 degreeC | Homo sapiens | 5 | ALA4725299 | cell-free format | Scientific Literature | |
4. | ALA4727276 | A | Agonist activity at human NMUR1 expressed in CHO cells at 100 nM by calcium mobilization assay relative to control | Homo sapiens | 2 | ALA4725299 | cell-based format | Scientific Literature | |
5. | ALA4727277 | A | Agonist activity at human NMUR2 expressed in CHO cells at 100 nM by calcium mobilization assay | Homo sapiens | 1 | ALA4725299 | cell-based format | Scientific Literature | |
6. | ALA4727282 | A | Stability of the compound in 25% human serum assessed as intact residual rate at 50 uM incubated for 180 mins at 37 degreeC | Homo sapiens | 3 | ALA4725299 | cell-free format | Scientific Literature |