# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA637115 | P | Solubility in Kreb-Heinsleit buffer. | 3 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA637117 | P | Solubility in deionized water. | 3 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA750971 | B | Ability to stimulate biochemical responses in cell lines expressing muscarinic A9 L receptor sub types | 9 | cell-based format | Scientific Literature | |||
4. | ALA744227 | F | Agonistic activity against M1 muscarinic receptor expressed in A9 L cells. | 16 | cell-based format | Scientific Literature | |||
5. | ALA744228 | F | Agonistic activity against M1 muscarinic receptor expressed in NIH 3T3 cells | 3 | cell-based format | Scientific Literature | |||
6. | ALA744770 | B | Binding affinity towards M1 muscarinic receptor expressed in A9 L cells by displacing [3H](R)-QNB radioligand. | 21 | cell-based format | Scientific Literature | |||
7. | ALA744923 | F | Percentage stimulation above basal levels at 100 uM expressed relative to the carbachol response. | 15 | assay format | Scientific Literature | |||
8. | ALA745727 | F | Maximal level of stimulation as a percentage above basal levels. | 17 | assay format | Scientific Literature | |||
9. | ALA746255 | B | Effective concentration was evaluated against Muscarinic acetylcholine receptor M1 expressed in A9 L cells | 9 | cell-based format | Scientific Literature | |||
10. | ALA746411 | B | Inhibition of [3H](R)-QNB to Muscarinic acetylcholine receptor M1 expressed in A9 L cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
11. | ALA745521 | B | Ability to stimulate biochemical responses in cell lines expressing muscarinic A9 L receptor sub types; no significant change from basal levels | 2 | cell-based format | Scientific Literature | |||
12. | ALA752408 | B | Effective concentration was evaluated against Muscarinic acetylcholine receptor M3 expressed in A9 L cells; Not calculable due to inconsistent dose response curves from assay to assay | 2 | cell-based format | Scientific Literature | |||
13. | ALA752413 | B | Compound was tested for binding inhibition of [3H](R)-QNB to Muscarinic acetylcholine receptor M3 expressed in A9 L cells | 7 | cell-based format | Scientific Literature | |||
14. | ALA747478 | F | Ability to inhibit the formation of cAMP stimulated by forskolin in A9 L cells expressing in Muscarinic acetylcholine receptor M4; Not determined | 3 | cell-based format | Scientific Literature | |||
15. | ALA749229 | F | Agonist activity against M4 muscarinic receptor expressed in RBL-2H3 Mast cells. | 11 | cell-based format | Scientific Literature | |||
16. | ALA857188 | B | Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M4 expressed in A9 L cells | 3 | cell-based format | Scientific Literature | |||
17. | ALA746457 | B | Compound was tested for binding inhibition of [3H](R)-QNB to Muscarinic acetylcholine receptor M4 expressed in A9 L cells | 7 | cell-based format | Scientific Literature | |||
18. | ALA747125 | B | Ability to stimulate biochemical responses in A9 L cell lines expressing Muscarinic acetylcholine receptor M5; Not calculatable due to inconsistent dose response curves from assay to assay | 1 | cell-based format | Scientific Literature | |||
19. | ALA747166 | F | Maximal level of stimulation as a percentage above basal levels. | 4 | assay format | Scientific Literature | |||
20. | ALA749968 | F | Ability to inhibit the formation of cAMP stimulated by forskolin in A9 L cells expressing Muscarinic acetylcholine receptor M2 | 4 | cell-based format | Scientific Literature |