| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4026494 | B | Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in presence of [3H]SAM by microbeta counting method | Rattus norvegicus | 18 | ALA4024748 | assay format | Scientific Literature | |
| 2. | ALA4026496 | B | Uncompetitive inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as substrate in presence of varying concentrations of [3H]SAM | Rattus norvegicus | 1 | ALA4024748 | assay format | Scientific Literature | |
| 3. | ALA4026497 | B | Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Rattus norvegicus | 1 | ALA4024748 | assay format | Scientific Literature | |
| 4. | ALA4026498 | B | Binding affinity to rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) at 200 uM by 1D 1H CPMG-NMR spectroscopic method | Rattus norvegicus | 3 | ALA4024748 | assay format | Scientific Literature | |
| 5. | ALA4026499 | B | Binding affinity to rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) at 200 uM by STD-NMR spectroscopic method | Rattus norvegicus | 3 | ALA4024748 | assay format | Scientific Literature | |
| 6. | ALA4026500 | B | Non-competitive inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) in presence of varying concentrations of biotinylated H4 peptide (1 to 21 residues) substrate and fixed [3H]SAM concentration | Rattus norvegicus | 1 | ALA4024748 | assay format | Scientific Literature | |
| 7. | ALA4026501 | B | Inhibition of PRMT3 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 8. | ALA4026502 | B | Inhibition of PRMT4 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 9. | ALA4026503 | B | Inhibition of PRMT5 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 10. | ALA4026504 | B | Inhibition of PRMT6 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 11. | ALA4026505 | B | Inhibition of PRMT8 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 12. | ALA4026506 | B | Inhibition of DOT1L (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 60 mins by Alpha screen assay | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 13. | ALA4026507 | B | Inhibition of EZH2 (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 60 mins by radioisotope assay | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 14. | ALA4026508 | B | Inhibition of DNMT3A/3L (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 60 mins by radioisotope assay | Homo sapiens | 1 | ALA4024748 | protein complex format | Scientific Literature | |
| 15. | ALA4026509 | B | Inhibition of DNMT1 (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 60 mins by radioisotope assay | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 16. | ALA4026510 | B | Inhibition of G9a (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 17. | ALA4026511 | B | Inhibition of PRDM9 (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 18. | ALA4026512 | B | Inhibition of SMYD2 (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 240 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 19. | ALA4026513 | B | Inhibition of SUV39H1 (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 20. | ALA4026514 | B | Inhibition of DOT1L (unknown origin) at 100 uM incubated for 15 mins followed by substrate addition measured after 60 mins by Alpha screen assay | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature |
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