# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4019800 | ADME | Efflux ratio of apparent permeability in human Caco2 cells | Homo sapiens | 4 | ALA4017519 | cell-based format | Scientific Literature | |
2. | ALA4019801 | ADME | Apparent permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 4 | ALA4017519 | cell-based format | Scientific Literature | |
3. | ALA4019803 | Binding | Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin peptide as substrate by TR-FRET assay | Homo sapiens | 34 | ALA4017519 | assay format | Scientific Literature | |
4. | ALA4019804 | Binding | Binding affinity to LSD1 (unknown origin) by SPR analysis | Homo sapiens | 33 | ALA4017519 | single protein format | Scientific Literature | |
5. | ALA4019805 | Binding | Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli at 30 uM after 30 mins using histone H3(1-21)K4(Me1) biotin peptide as substrate by TR-FRET assay relative to control | Homo sapiens | 34 | ALA4017519 | assay format | Scientific Literature | |
6. | ALA4019806 | Binding | Inhibition of LSD1 in human THP1 cells assessed as induction of CD86 expression after 48 hrs by flow cytometric analysis | Homo sapiens | 3 | ALA4017519 | cell-based format | Scientific Literature | |
7. | ALA4019810 | Binding | Inhibition of human hERG by patch clamp method | Homo sapiens | 4 | ALA4017519 | assay format | Scientific Literature | |
8. | ALA4019812 | ADME | Intrinsic clearance in mouse liver microsomes assessed per 10'6 cells | Mus musculus | 4 | ALA4017519 | assay format | Scientific Literature | |
9. | ALA4019813 | ADME | Half life in mouse liver microsomes | Mus musculus | 4 | ALA4017519 | assay format | Scientific Literature |