| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4057172 | B | Inhibition of AKT1 (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4057173 | P | Lipophilicity, log D of the compound | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4057174 | F | Inhibition of human recombinant BMP6-stimulated hepcidin mRNA expression in human HepG2 cells after 6 hrs by qRT-PCR analysis | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 4. | ALA4057175 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 1 uM after 0.5 hrs by LC-MS/MS analysis | Mus musculus | 3 | assay format | Scientific Literature | ||
| 5. | ALA4057176 | A | Metabolic stability in mouse liver microsomes assessed as UGT-mediated compound hydrolysis by measuring parent compound remaining at 1 uM after 0.5 hrs by LC-MS/MS analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
| 6. | ALA4057178 | A | Cmax in C57BL/6J mouse at 30 mg/kg, po by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA4057180 | A | Tmax in C57BL/6J mouse at 30 mg/kg, po by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA4057182 | A | AUC in C57BL/6J mouse at 30 mg/kg, po by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA4057186 | F | Antiinflammatory activity in C57BL/6J mouse assessed as reduction in recombinant mouse IL-6 induced serum hepcidin level at 30 mg/kg, po pretreated for 30 mins followed by IL-6 challenge measured after 4 hrs by LC-MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA4057188 | B | Inhibition of AKT2 (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4057189 | B | Inhibition of AKT3 (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4057190 | B | Inhibition of MSK1 (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4057191 | B | Inhibition of MSK2 (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4057192 | B | Inhibition of p70S6K (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4057193 | B | Inhibition of PKA (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4057194 | B | Inhibition of PKC-alpha (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4057195 | B | Inhibition of PKC-beta2 (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4057196 | B | Inhibition of PKC-beta1 (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4057197 | B | Inhibition of PKC-delta (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4057198 | B | Inhibition of PKC-epsilon (unknown origin) at 0.45 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!