# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4009141 | B | Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation counting | Cavia porcellus | 26 | cell membrane format | Scientific Literature | ||
2. | ALA4009142 | B | Displacement of [3H]DAMGO from mu-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation counting | Cavia porcellus | 16 | cell membrane format | Scientific Literature | ||
3. | ALA4009144 | B | Displacement of [3H]DPDPE from delta-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation counting | Cavia porcellus | 25 | cell membrane format | Scientific Literature | ||
4. | ALA4009146 | B | Displacement of [3H]-(+)-pentazocine from sigma1-type opioid receptor in guinea pig cortex membranes at 1 uM after 120 mins by solid scintillation counting | Cavia porcellus | 24 | cell membrane format | Scientific Literature | ||
5. | ALA4009148 | B | Displacement of [3H]-DTG from sigma 2 receptor in rat liver membranes at 1 uM after 120 mins by scintillation counting | Rattus norvegicus | 23 | cell membrane format | Scientific Literature | ||
6. | ALA4009150 | B | Displacement of [3H]-(+)-MK 801 from PCP binding site of NMDA receptor in pig brain cortex membranes at 10 uM after 120 mins by solid scintillation counting | Sus scrofa | 23 | cell membrane format | Scientific Literature | ||
7. | ALA4009152 | F | Agonist activity at recombinant human kappa-type opioid receptor expressed in HEK293 cells after 30 mins by [35S]GTPgammaS binding assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
8. | ALA4009153 | F | Agonist activity at recombinant human kappa-type opioid receptor expressed in HEK293 cells at 1 uM after 30 mins by [35S]GTPgammaS binding assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
9. | ALA4009187 | F | Antiinflammatory activity in arachidonic acid-induced ear dermatitis ICR mouse model assessed as reduction in ear swelling at 0.1 mg administered twice tropically 30 mins prior and 15 mins after arachidonic acid addition measured 60 mins post arachidonic acid challenge relative to control | Mus musculus | 14 | assay format | Scientific Literature | ||
10. | ALA4009188 | F | Antiinflammatory activity in arachidonic acid-induced ear dermatitis ICR mouse model assessed as reduction in ear swelling at 0.3 mg administered twice tropically 30 mins prior and 15 mins after arachidonic acid addition measured 60 mins post arachidonic acid challenge relative to control | Mus musculus | 13 | assay format | Scientific Literature | ||
11. | ALA4009189 | F | Antiinflammatory activity in arachidonic acid-induced ear dermatitis ICR mouse model assessed as reduction in ear swelling at 1 mg administered twice tropically 30 mins prior and 15 mins after arachidonic acid addition measured 60 mins post arachidonic acid challenge relative to control | Mus musculus | 13 | assay format | Scientific Literature | ||
12. | ALA4009190 | F | Antiinflammatory activity in arachidonic acid-induced ear dermatitis ICR mouse model assessed as reduction in ear swelling at 3 mg administered twice tropically 30 mins prior and 15 mins after arachidonic acid addition measured 60 mins post arachidonic acid challenge relative to control | Mus musculus | 14 | assay format | Scientific Literature | ||
13. | ALA4009210 | F | Antinociceptive activity in sc dosed mouse model of acetic acid-induced writhing | Mus musculus | 3 | organism-based format | Scientific Literature | ||
14. | ALA4009211 | T | CNS toxicity in sc dosed mouse model of acetic acid-induced writhing assessed as lowest dose causing side effects | Mus musculus | 3 | organism-based format | Scientific Literature |