| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4038532 | Functional | Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay | Homo sapiens | 8 | ALA4038272 | cell-based format | Scientific Literature | |
| 2. | ALA4038533 | Functional | Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by CCK-8 assay | Homo sapiens | 8 | ALA4038272 | cell-based format | Scientific Literature | |
| 3. | ALA4038534 | ADME | Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay | Homo sapiens | 8 | ALA4038272 | cell-based format | Scientific Literature | |
| 4. | ALA4038535 | Functional | Resistant factor, ratio of IC50 for human Bel7402/5-FU cells to IC50 for human Bel7402 cells | Homo sapiens | 8 | ALA4038272 | assay format | Scientific Literature | |
| 5. | ALA4038536 | Functional | Cell cycle arrest in human Bel7402/5-FU cells assessed as accumulation at G1 phase at 0.1 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 52.21%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 6. | ALA4038537 | Functional | Cell cycle arrest in human Bel7402/5-FU cells assessed as accumulation at S phase at 0.1 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 12.62%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 7. | ALA4038538 | Functional | Cell cycle arrest in human Bel7402/5-FU cells assessed as accumulation at G2 phase at 0.1 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 35.16%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 8. | ALA4038548 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as reduction in cell number at 0.1 uM after 24 hrs by Hoechst 33342 staining based fluorescent microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 9. | ALA4038549 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as morphological changes at 0.1 uM after 24 hrs by Hoechst 33342 staining based fluorescent microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 10. | ALA4038550 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as condensed nuclei at 0.1 uM after 24 hrs by Hoechst 33342 staining based fluorescent microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 11. | ALA4038560 | Functional | Induction of apoptosis in human Bel7402/5-FU cells at 0.1 uM after 24 hrs by Hoechst 33342 staining based fluorescent microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 12. | ALA4038564 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as live cells at 0.1 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 91.08%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 13. | ALA4038565 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as early apoptotic cells at 0.1 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 5.24%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 14. | ALA4038566 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as late apoptotic cells at 0.1 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 3%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 15. | ALA4038567 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as necrotic cells at 0.1 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 0.58%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 16. | ALA4038580 | Functional | Induction of microtubule disruption in human Bel7402/5-FU cells at 0.1 uM after 24 to 48 hrs by DAPI staining based immunofluorescence microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 17. | ALA4038584 | Functional | Reduction in microtubule density in human Bel7402/5-FU cells at 0.1 uM after 24 to 48 hrs by DAPI staining based immunofluorescence microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 18. | ALA4038588 | Functional | Antimigratory activity in human Bel7402/5-FU cells at 0.1 uM after 24 hrs by wound healing assay | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 19. | ALA4038592 | Functional | Effect on CDK1 expression in human Bel7402/5-FU cells assessed as ratio of CDK1 to beta-actin level at 0.1 uM after 48 hrs by Western blot analysis (Rvb = 0.33 No_unit) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
| 20. | ALA4038593 | Functional | Effect on CDK2 expression in human Bel7402/5-FU cells assessed as ratio of CDK2 to beta-actin level at 0.1 uM after 48 hrs by Western blot analysis (Rvb = 0.43 No_unit) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature |
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