| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4037524 | B | Antagonist activity at TEV protease cleavage site linked GAL4-VP16-fused recombinant human CXCR2 expressed in cells assessed as inhibition of TEV protease tagged human CXCL1-stimulated beta-arrestin recruitment by CCF4-AM-fluorescence based FRET assay | Homo sapiens | 67 | cell-based format | Scientific Literature | ||
| 2. | ALA4037525 | P | Solubility of compound in fasted state simulated intestinal fluid measured after 4 hrs | 33 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4037527 | A | Passive permeability in MDCK2-MDR1 cells transduced with BacMam2-BCRP at 3 uM after 90 mins by Transwell assay | Canis lupus familiaris | 33 | cell-based format | Scientific Literature | ||
| 4. | ALA4037528 | B | Antagonist activity at CXCR2 in human whole blood assessed as inhibition of GROalpha-stimulated CD11b upregulation preincubated for 15 mins followed by GROalpha stimulation measured after 15 mins by FITC-staining based FACS analysis | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 5. | ALA4037616 | A | Ratio of passive permeability in presence of dual P-gp/BCRP inhibitor GF120918 to absence of GF120918 in MDCK2-MDR1 cells transduced with BacMam2-BCRP at 3 uM after 90 mins by Transwell assay | Canis lupus familiaris | 9 | cell-based format | Scientific Literature |
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