# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4017021 | Binding | Inhibition of HDAC1/2/3/6 in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay | Homo sapiens | 17 | ALA4014348 | cell-based format | Scientific Literature | |
2. | ALA4017022 | Binding | Inhibition of HDAC1/2/3/6 in human A2780cisR cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay | Homo sapiens | 17 | ALA4014348 | cell-based format | Scientific Literature | |
3. | ALA4017023 | Binding | Inhibition of HDAC1/2/3/6 in human Cal27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay | Homo sapiens | 17 | ALA4014348 | cell-based format | Scientific Literature | |
4. | ALA4017024 | Functional | Cytotoxicity against human A2780cisR cells assessed as cell survival after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4014348 | cell-based format | Scientific Literature | |
5. | ALA4017025 | Functional | Cytotoxicity against human A2780 cells assessed as cell survival after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4014348 | cell-based format | Scientific Literature | |
6. | ALA4017026 | Functional | Cytotoxicity against human CAL27 cells assessed as cell survival after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4014348 | cell-based format | Scientific Literature | |
7. | ALA4017027 | Binding | Inhibition of C-terminal FLAG/His-tagged recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 5 | ALA4014348 | cell-based format | Scientific Literature | |
8. | ALA4017028 | Binding | Inhibition of N-terminal GST-tagged recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 5 | ALA4014348 | cell-based format | Scientific Literature | |
9. | ALA4017029 | Binding | Inhibition of full length human recombinant C-terminal His-tagged HDAC3/NcoR2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 5 | ALA4014348 | cell-based format | Scientific Literature | |
10. | ALA4017030 | Binding | Inhibition of full length human recombinant C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 5 | ALA4014348 | cell-based format | Scientific Literature | |
11. | ALA4017031 | Binding | Inhibition of human recombinant HDAC8 expressed in Escherichia coli using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 5 | ALA4014348 | assay format | Scientific Literature | |
12. | ALA4017045 | Binding | Inhibition of HDAC1/2/3/6 in human Cal27CisR cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay | Homo sapiens | 17 | ALA4014348 | cell-based format | Scientific Literature | |
13. | ALA4017046 | Functional | Cytotoxicity against human Cal27CisR cells assessed as cell survival after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4014348 | cell-based format | Scientific Literature |