| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4019942 | Functional | Antiproliferative activity against human U87MG cells at 1 nM to 100 uM after 24 hrs by MTS assay | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 2. | ALA4019945 | Binding | Inhibition of MDM2/MDMX in human SH-SY5Y cells assessed as accumulation of p53 at 1 uM after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 3. | ALA4019946 | Binding | Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic assay | Homo sapiens | 15 | ALA4017523 | cell-based format | Scientific Literature | |
| 4. | ALA4019947 | Binding | Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic assay | Homo sapiens | 15 | ALA4017523 | cell-based format | Scientific Literature | |
| 5. | ALA4019961 | Binding | Inhibition of MDM2/MDMX in human SH-SY5Y cells assessed as increase in MDM2 mRNA levels at 1 uM after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 6. | ALA4019962 | Binding | Inhibition of MDM2/MDMX in human SH-SY5Y cells assessed as increase in PUMA mRNA levels at 1 uM after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 7. | ALA4019963 | Binding | Inhibition of MDM2/MDMX in human SH-SY5Y cells assessed as increase in p21 mRNA levels at 1 uM after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 8. | ALA4019964 | Functional | Antiproliferative activity against human SH-SY5Y cells at 1 uM after 24 hrs by MTS assay relative to control | Homo sapiens | 3 | ALA4017523 | cell-based format | Scientific Literature | |
| 9. | ALA4019967 | Functional | Antiproliferative activity against human SH-SY5Y cells after 24 hrs by MTS assay | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 10. | ALA4019968 | Functional | Antiproliferative activity against human SH-SY5Y cells at 1 nM to 100 uM after 72 hrs by neutral red dye-based assay | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 11. | ALA4019969 | Functional | Antiproliferative activity against human U87MG cells at 1 nM to 100 uM after 72 hrs by neutral red dye-based assay | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 12. | ALA4019970 | Functional | Antiproliferative activity against human U87MG derived cancer stem cells after 7 days by MTS assay | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 13. | ALA4019971 | Functional | Antiproliferative activity against human SH-SY5Y derived cancer stem cells after 7 days by MTS assay | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 14. | ALA4019972 | Functional | Antiproliferative activity against human U87MG derived cancer stem cells at 100 uM after 7 days by MTS assay relative to control | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 15. | ALA4019973 | Functional | Antiproliferative activity against human SH-SY5Y derived cancer stem cells at 100 uM after 7 days by MTS assay relative to control | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 16. | ALA4019974 | Functional | Induction of apoptosis in human SH-SY5Y cells assessed as viable cells at 1 uM after 24 hrs by annexin staining based fluorescence assay (Rvb = 93.10%) | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 17. | ALA4019975 | Functional | Induction of apoptosis in human SH-SY5Y cells assessed as early apoptotic cells at 1 uM after 24 hrs by annexin staining based fluorescence assay (Rvb = 4.94%) | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 18. | ALA4019976 | Functional | Induction of apoptosis in human SH-SY5Y cells assessed as late apoptotic cells at 1 uM after 24 hrs by annexin staining based fluorescence assay (Rvb = 1.65%) | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 19. | ALA4019977 | Functional | Induction of apoptosis in human SH-SY5Y cells assessed as necrotic cells at 1 uM after 24 hrs by annexin staining based fluorescence assay (Rvb = 0.13%) | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
| 20. | ALA5164644 | Binding | Inhibition of MDM4/p53 interaction in human SH-SY5Y cells using TMB as substrate incubated for 10 mins by quantitative immuno-enzymatic assay | Homo sapiens | 2 | ALA5154862 | cell-based format | Scientific Literature |
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