#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4054819	Binding	Inhibition of GST-tagged JAK1 (unknown origin) after 3 hrs by Caliper assay	Homo sapiens	33	ALA4052645	single protein format	Scientific Literature
2.	ALA4054820	Binding	Inhibition of His-tagged TYK2 (unknown origin) after 3 hrs by Caliper assay	Homo sapiens	33	ALA4052645	single protein format	Scientific Literature
3.	ALA4054821	Binding	Inhibition of JAK3 (unknown origin) using CSKtide as substrate after 30 mins in presence of [gamma33P]ATP by liquid scintillation counting method	Homo sapiens	33	ALA4052645	single protein format	Scientific Literature
4.	ALA4054822	ADME	Inhibition of GST-tagged JAK2 (unknown origin) after 3 hrs by Caliper assay	Homo sapiens	33	ALA4052645	single protein format	Scientific Literature
5.	ALA4054823	Unassigned	Selectivity ratio of IC50 for JAK2 dependent EPO-induced STAT5A phosphorylation in human TF1 cells to IC50 for JAK1/JAK3 dependent IL2-induced STAT3 phosphorylation in human PBMC derived T-cells	Homo sapiens	28	ALA4052645	cell-based format	Scientific Literature
6.	ALA4054824	Binding	Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-2 induced IFN-gamma production after 18 hrs by ELISA	Homo sapiens	33	ALA4052645	protein complex format	Scientific Literature
7.	ALA4054825	ADME	Oral bioavailability in mouse	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
8.	ALA4054827	Functional	In vivo inhibition of JAK1/JAK3 in Balb/c mouse assessed as reduction in IL15-induced STAT5 phosphorylation at 10 mg/kg,po administered as single dose after 24 hrs	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
9.	ALA4054830	ADME	Clearance of compound in mouse relative to hepatic blood flow	Mus musculus	1	ALA4052645	assay format	Scientific Literature
10.	ALA4054831	ADME	Clearance of compound in mouse	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
11.	ALA4054832	ADME	Drug concentration in mouse after 24 hrs	Mus musculus	1	ALA4052645	assay format	Scientific Literature
12.	ALA4054833	Functional	In vivo inhibition of JAK1/JAK3 in Balb/c mouse assessed as reduction in IL15-induced STAT5 phosphorylation at 5 mg/ml, po after 4 hrs	Mus musculus	2	ALA4052645	organism-based format	Scientific Literature
13.	ALA4054834	Functional	Antiarthritic activity in collagen-induced arthritis mouse model assessed as reduction in inflammation at 10 mg/kg, po qd measured up to 41 days	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
14.	ALA4054835	ADME	Drug concentration in mouse at 10 mg/kg, po qd after 24 hrs	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
15.	ALA4054836	Functional	Antiarthritic activity in collagen-induced arthritis mouse model assessed as reduction in inflammation at 2 mg/kg, po qd measured up to 41 days	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
16.	ALA4054837	ADME	Drug concentration in mouse at 2 mg/kg, po qd after 24 hrs	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
17.	ALA4054840	Functional	Antiarthritic activity in collagen-induced mouse model assessed as increase in bone resorption at 10 mg/kg, po qd up to 41 days	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
18.	ALA4054841	Functional	Antiarthritic activity in collagen-induced mouse model assessed as increase in bone resorption at 2 mg/kg, po qd up to 41 days	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
19.	ALA4054842	Toxicity	Toxicity in collagen-induced arthritis mouse model at 50 mg/kg, po qd	Mus musculus	1	ALA4052645	organism-based format	Scientific Literature
20.	ALA4054843	Binding	Inhibition of human ERG by patch clamp method	Homo sapiens	2	ALA4052645	assay format	Scientific Literature