| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4010769 | Binding | Inhibition of recombinant human TACE catalytic domain using Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate after 2 hrs by fluorescence assay | Homo sapiens | 40 | ALA4007472 | single protein format | Scientific Literature | |
| 2. | ALA4010770 | ADME | Stability in human liver microsomes assessed as parent compound remaining at 1 uM after 15 mins by LC-MS/MS analysis | Homo sapiens | 13 | ALA4007472 | assay format | Scientific Literature | |
| 3. | ALA4010777 | Binding | Inhibition of TACE in NHEK assessed as reduction in LPS/TPA-stimulated TNFalpha production preincubated for 1 hr followed by LPS/TPA stimulation for 24 hrs by HTRF assay | Homo sapiens | 11 | ALA4007472 | single protein format | Scientific Literature | |
| 4. | ALA4010781 | Physicochemical | Aqueous solubility of the compound | 11 | ALA4007472 | small-molecule physicochemical format | Scientific Literature |
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