#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4015669	Binding	Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA duplex after 1 hr by scintillation counting method	Homo sapiens	11	ALA4014314	single protein format	Scientific Literature
2.	ALA4015670	Binding	Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex at CpG site after 1 hr by fluorescence assay	Homo sapiens	11	ALA4014314	single protein format	Scientific Literature
3.	ALA4015671	Binding	Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex at CpG site at 32 uM after 1 hr by fluorescence assay relative to control	Homo sapiens	50	ALA4014314	single protein format	Scientific Literature
4.	ALA4015672	Binding	Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex at CpG site at 10 uM after 1 hr by fluorescence assay relative to control	Homo sapiens	50	ALA4014314	single protein format	Scientific Literature
5.	ALA4015673	Binding	Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA duplex at 32 uM after 1 hr by scintillation counting method relative to control	Homo sapiens	50	ALA4014314	single protein format	Scientific Literature
6.	ALA4015674	Binding	Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA duplex at 100 uM after 1 hr by scintillation counting method relative to control	Homo sapiens	50	ALA4014314	single protein format	Scientific Literature
7.	ALA4015675	Binding	Inhibition of DNMT in human KG1 cells assessed as luciferase gene driven CMV promoter demethylation by measuring fold increase in luciferase reactivation at 5 uM after 24 hrs by luciferase reporter gene assay relative to control	Homo sapiens	3	ALA4014314	cell-based format	Scientific Literature
8.	ALA4015676	Binding	Inhibition of DNMT in human KG1 cells assessed as luciferase gene driven CMV promoter demethylation by measuring fold increase in luciferase reactivation at 1 uM after 24 hrs by luciferase reporter gene assay relative to control	Homo sapiens	3	ALA4014314	cell-based format	Scientific Literature
9.	ALA4015680	Binding	Inhibition of DNMT in human KG1 cells assessed as nucleosome occupancy at CMV promoter by measuring increase in luciferase signal at 5 uM after 24 hrs by NOMe-Seq method relative to control	Homo sapiens	2	ALA4014314	cell-based format	Scientific Literature
10.	ALA4015681	Toxicity	Toxicity in human KG1 cells assessed as effect on cell viability at 5 uM after 24 hrs by ATPLite assay	Homo sapiens	2	ALA4014314	cell-based format	Scientific Literature
11.	ALA4015682	Binding	Inhibition of DNMT in human KG1 cells assessed as CpG site demethylation at CMV promoter at 5 uM after 24 hrs by NOMe-Seq method relative to control	Homo sapiens	2	ALA4014314	cell-based format	Scientific Literature
12.	ALA4015683	Binding	Inhibition of DNMT in human KG1 cells assessed as increase in DNA accessibility by opening the chromatin at 5 uM after 24 hrs by NOMe-Seq method relative to control	Homo sapiens	2	ALA4014314	cell-based format	Scientific Literature
13.	ALA4015684	Binding	Inhibition of DNMT in human HCT116 cells assessed as demethylation of CDKN2A promoter at 100 nM after 3 days by COBRA analysis relative to control	Homo sapiens	3	ALA4014314	cell-based format	Scientific Literature
14.	ALA4015685	Binding	Inhibition of DNMT in human HCT116 cells assessed as demethylation of CDKN2A promoter at 100 nM after 7 days by COBRA analysis relative to control	Homo sapiens	3	ALA4014314	cell-based format	Scientific Literature
15.	ALA4015688	Binding	Binding affinity to 265 bp pBS DNA at 0.01 to 10 uM after 15 mins using 3'-end labeled using alpha-[32P]-dATP by DNase I footprinting assay	Not specified	1	ALA4014314	assay format	Scientific Literature
16.	ALA4015689	Binding	Binding affinity to 5'-TATATACGTACTGTGTTTTCACAGTACGTATATA-3' CpG site hairpin duplex DNA (unknown origin) assessed as change in melting temperature at 10 uM	Not specified	1	ALA4014314	assay format	Scientific Literature
17.	ALA4015690	Binding	Binding affinity to 117 bp pBS DNA at 0.01 to 10 uM after 15 mins using 3'-end labeled using alpha-[32P]-dATP by DNase I footprinting assay	Not specified	1	ALA4014314	assay format	Scientific Literature
18.	ALA4015692	Binding	Binding affinity to 5'-TATATACGTACGGTGTTTTCACCGTACGTATATA-3' CpG site hairpin duplex DNA (unknown origin) assessed as change in melting temperature at 10 uM	Not specified	1	ALA4014314	assay format	Scientific Literature