# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3999065 | B | Inhibition of 5'-biotin-labeled c-Myc Pu18 G-quadruplex DNA (unknown origin) interaction with His-tagged NM23-H2 at 20 uM preincubated with NM23-H2 for 1 hr followed by addition of DNA measured after overnight incubation by ELISA | Not specified | 21 | ALA3997802 | assay format | Scientific Literature | |
2. | ALA3999067 | B | Inhibition of thiazole orange binding to c-Myc Pu18 G-quadruplex DNA (unknown origin) at 10 uM after 30 secs by fluorescence spectrophotometric method | Not specified | 8 | ALA3997802 | assay format | Scientific Literature | |
3. | ALA3999068 | B | Inhibition of thiazole orange binding to c-Myc Pu27 G-quadruplex DNA (unknown origin) at 10 uM after 30 secs by fluorescence spectrophotometric method | Not specified | 8 | ALA3997802 | assay format | Scientific Literature | |
4. | ALA5119287 | B | Inhibition of HDAC in human HeLa nuclear extract at 10 uM incubated for 30 mins by fluorescence-based Glo-luminescence assay | Homo sapiens | 5 | ALA5113518 | cell-based format | Scientific Literature | |
5. | ALA5119288 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA Pu22 (unknown origin) by fluorescence quench assay | Not specified | 17 | ALA5113518 | nucleic acid format | Scientific Literature | |
6. | ALA5119290 | B | Binding affinity to 5' FAM and 3' TAMRA-labeled c-myc G4-quadruplex DNA Pu22 (unknown origin) assessed as change in melting temperature at 1 uM by fluorescence resonance energy transfer assay | Not specified | 19 | ALA5113518 | nucleic acid format | Scientific Literature | |
7. | ALA5119299 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA Pu22 (unknown origin) assessed as dissociation constant by surface plasmon resonance assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
8. | ALA5119300 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA HRAS (unknown origin) assessed as dissociation constant by surface plasmon resonance assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
9. | ALA5119301 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA HTG21 (unknown origin) assessed as dissociation constant by surface plasmon resonance assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
10. | ALA5119302 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA duplex (unknown origin) assessed as dissociation constant at 10 uM by surface plasmon resonance assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
11. | ALA5119303 | B | Binding affinity to 5' FAM and 3' TAMRA-labeled c-myc G4-quadruplex DNA HRAS (unknown origin) assessed as change in melting temperature by fluorescence resonance energy transfer assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
12. | ALA5119304 | B | Binding affinity to 5' FAM and 3' TAMRA-labeled c-myc G4-quadruplex DNA HTG21 (unknown origin) assessed as change in melting temperature by fluorescence resonance energy transfer assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
13. | ALA5119305 | B | Binding affinity to 5' FAM and 3' TAMRA-labeled c-myc G4-quadruplex DNA duplex (unknown origin) assessed as change in melting temperature by fluorescence resonance energy transfer assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
14. | ALA5119306 | B | Stabilization of DNA Pu22 (unknown origin ) single strand assessed as G4-quadruplex formation up to 30 uM in presence of potassium ions by spectrum based circular dichroism analysis | Not specified | 2 | ALA5113518 | assay format | Scientific Literature | |
15. | ALA5119307 | B | Stabilization of DNA Pu22 (unknown origin ) single strand assessed as G4-quadruplex formation in absence of potassium ions by spectrum based circular dichroism analysis | Not specified | 2 | ALA5113518 | assay format | Scientific Literature | |
16. | ALA5119308 | B | Stabilization of FAM-labeled DNA Pu22 (unknown origin ) double strand assessed as G4-quadruplex formation incubated for 30 mins in presence of potassium ions by electrophoresis mobility shift assay | Not specified | 3 | ALA5113518 | assay format | Scientific Literature | |
17. | ALA5119310 | B | Inhibition of HDAC in human MDA-MB-231 cells incubated for 45 mins by luminescence assay | Homo sapiens | 3 | ALA5113518 | cell-based format | Scientific Literature | |
18. | ALA5119321 | F | Cytotoxicity against human MDA-MB-231 cells harboring wild type BRCA1 and wild BRCA2 assessed as reduction in cell viability | Homo sapiens | 3 | ALA5113518 | cell-based format | Scientific Literature | |
19. | ALA5119322 | F | Cytotoxicity against human MDA-MB-468 cells harboring wild type BRCA1 and BRCA2 mutant reduction in assessed as cell viability | Homo sapiens | 3 | ALA5113518 | cell-based format | Scientific Literature | |
20. | ALA5119323 | F | Cytotoxicity against human SUM159PT cells harboring wild type BRCA1 and wild type BRCA2 assessed as reduction in cell viability | Homo sapiens | 3 | ALA5113518 | cell-based format | Scientific Literature |