| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4051302 | B | Agonist activity at human GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 2. | ALA4051303 | B | Agonist activity at human GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay relative to control | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 3. | ALA4051304 | F | Agonist activity at mouse GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium level after 5 mins by FLUO-4-AM dye-based FLIPR assay | Mus musculus | 30 | cell-based format | Scientific Literature | ||
| 4. | ALA4051305 | F | Agonist activity at mouse GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium level after 5 mins by FLUO-4-AM dye-based FLIPR assay relative to control | Mus musculus | 30 | cell-based format | Scientific Literature | ||
| 5. | ALA4051306 | P | Octanol-buffer partition coefficient, log D of the compound at pH 7.4 after 30 mins by LC-UV based shake-flask method | 19 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4051315 | A | Protein binding in mouse plasma assessed as unbound fraction after 24 hrs by equilibrium dialysis | Mus musculus | 5 | cell-free format | Scientific Literature | ||
| 7. | ALA4051316 | A | Clearance in mouse at 2.5 mg/kg, iv after 24 hrs | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA4051318 | A | Volume of distribution at steady state in mouse at 2.5 mg/kg, iv after 24 hrs | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 9. | ALA4051320 | A | Cmax in mouse at 5 mg/kg administered through oral gavage after 24 hrs | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 10. | ALA4051321 | A | Oral bioavailability in mouse at 5 mg/kg after 24 hrs | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 11. | ALA4051322 | A | Ratio of drug level in mouse brain to blood at 5 mg/kg administered through oral gavage after 2 hrs | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 12. | ALA4051331 | B | Agonist activity at mouse GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA4051332 | B | Agonist activity at mouse GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay relative to control | Mus musculus | 7 | cell-based format | Scientific Literature |
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