# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4014480 | Binding | Inhibition of ABCB1 in human MCF7/ADR cells assessed as potentiation of vinblastine-induced cytotoxicity by measuring vinblastine IC50 at IC10 after 7 days by SRB assay | Homo sapiens | 15 | ALA4014272 | cell-based format | Scientific Literature | |
2. | ALA4014481 | Functional | Growth inhibition of human MCF7 cells after 48 hrs by SRB assay | Homo sapiens | 16 | ALA4014272 | cell-based format | Scientific Literature | |
3. | ALA4014482 | Functional | Growth inhibition of human MCF7/ADR cells after 48 hrs by SRB assay | Homo sapiens | 17 | ALA4014272 | cell-based format | Scientific Literature | |
4. | ALA4014483 | Binding | Inhibition of ABCB1 in human MCF7/ADR cells assessed as potentiation of vinblastine-induced cytotoxicity at IC10 after 7 days by SRB assay relative to vinblastine alone | Homo sapiens | 13 | ALA4014272 | cell-based format | Scientific Literature | |
5. | ALA4014484 | Binding | Displacement of [3H]-azidopine from ABCB1 in human KBV1 cell membranes at IC50 incubated for 20 mins in dark followed by irradiation of UV-light measured after 20 mins by SDS-PAGE based autoradiography relative to control | Homo sapiens | 16 | ALA4014272 | cell-based format | Scientific Literature |