# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4055863 | B | Inhibition of Saccharomyces cerevisiae alpha-glucosidase pre-incubated for 10 mins before p-nitrophenyl beta-D-glucopyranoside substrate addition and measured every 30 secs for 35 mins post substrate addition | Saccharomyces cerevisiae | 13 | assay format | Scientific Literature | ||
2. | ALA4055864 | B | Inhibition of human recombinant PTP1B pre-incubated for 10 mins before pnitrophenyl phosphate substrate addition and measured every 30 secs for 10 mins | Homo sapiens | 13 | single protein format | Scientific Literature | ||
3. | ALA4181909 | B | Induction of AKT phosphorylation at Ser 473 residues in rat L6 cells by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
4. | ALA4181910 | F | Increase in glucose uptake in rat L6 cells at 25 uM after 4 hrs relative to control | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
5. | ALA4181912 | A | Cytotoxicity against rat L6 cells assessed as reduction in cell viability at 1 to 100 uM after 4 hrs by MTT assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4181913 | F | Increase in glucose uptake in rat L6 cells at <10 uM after 4 hrs | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
7. | ALA4181915 | F | Increase in glucose uptake in rat L6 cells at 25 uM treated for 4 hrs post 15 mins PI3K inhibitor wortmanin treatment | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
8. | ALA4181916 | F | Increase in glucose uptake in rat L6 cells at 25 uM treated for 4 hrs post 30 mins AMPK inhibitor compound C treatment | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
9. | ALA4181918 | B | Activation of AKT in rat L6 cells assessed as GSK3beta phosphorylation at Ser 9 residues at 12.5 to 25 uM by Western blot analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
10. | ALA4181919 | B | Induction of AMPK phosphorylation at Tyr 172 residues in rat L6 cells at 25 uM by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
11. | ALA4181920 | B | Activation of AMPK in rat L6 cells assessed as ACC phosphorylation at Ser 79 residues at 25 uM by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA4181923 | B | Activation of PI3K/AKT/AMPK in rat L6 cells transfected with mOrange dye-based IRAP assessed as increase in GLUT4 translocation at 25 uM measured every 5 mins for 30 mins by confocal microscopic analysis relative to basal control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
13. | ALA4181924 | B | Activation of PI3K/AKT/AMPK in rat L6 cells transfected with mOrange dye-based IRAP assessed as increase in GLUT4 translocation at 25 uM measured every 5 mins for 30 mins post 15 mins PI3K inhibitor wortmanin treatment by confocal microscopic analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
14. | ALA4181925 | B | Activation of PI3K/AKT/AMPK in rat L6 cells transfected with mOrange dye-based IRAP assessed as increase in GLUT4 translocation at 25 uM measured every 5 mins for 30 mins post 30 mins AMPK inhibitor compound C treatment by confocal microscopic analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
15. | ALA4181926 | A | Cytotoxicity against rat L6 cells assessed as reduction in cell viability at 25 uM after 4 hrs by MTT assay | Rattus norvegicus | 20 | cell-based format | Scientific Literature | ||
16. | ALA4181927 | F | Increase in glucose uptake in rat L6 cells at 10 to 25 uM after 4 hrs | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
17. | ALA4181928 | F | Increase in glucose uptake in rat L6 cells at 25 to 100 uM after 4 hrs | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
18. | ALA4181929 | F | Increase in glucose uptake in rat L6 cells at 25 uM after 2 to 4 hrs | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
19. | ALA4181930 | B | Induction of AKT phosphorylation at Ser 473 residues in rat L6 cells at 12.5 to 25 uM by Western blot analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
20. | ALA5224129 | F | Antibacterial activity against methicillin resistant Staphylococcus aureus | Staphylococcus aureus | 3 | organism-based format | Scientific Literature |