| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4056012 | B | Agonist activity at FXR in human Caco2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA4056013 | B | Agonist activity at FXR in human Hepg2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4056015 | B | Agonist activity at FXR in rat primary hepatocytes assessed as increase in BSEP mRNA expression at 50 uM | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4056016 | B | Agonist activity at FXR in rat primary hepatocytes assessed as increase in SHP mRNA expression at 50 uM | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4056017 | B | Agonist activity at FXR in rat primary hepatocytes assessed as reduction in CYP7A1 mRNA expression at 50 uM | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4056018 | A | Cytotoxicity against human Caco2 cells at 100 uM incubated for 24 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4056019 | A | Drug uptake in human Caco2 cells at 20 and 50 uM by LC-MS/MS method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4056020 | A | Drug uptake in human Caco2 cells at 20 and 50 uM by LC-MS/MS method after 3 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4056022 | A | Apparent permeability from apical side to basolateral side in human Caco2 cells at 20 uM by LC-MS/MS method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4056023 | A | Apparent permeability from apical side to basolateral side in human Caco2 cells at 50 uM by LC-MS/MS method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4056024 | A | Apparent permeability from basolateral to apical side in human Caco2 cells at 20 uM by LC-MS/MS method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4056025 | A | Apparent permeability from basolateral to apical side in human Caco2 cells at 50 uM by LC-MS/MS method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4056026 | A | Efflux ratio in human Caco2 cells at 20 uM by LC-MS/MS method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4056027 | A | Efflux ratio in human Caco2 cells at 50 uM by LC-MS/MS method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4056028 | A | Drug accumulation in C57BL/6 mouse ileum at 100 mg/kg, ig for 5 days by LC-MS/MS method | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA4056032 | F | Increase in FXR mRNA expression in C57BL/6 mouse ileum at 100 mg/kg, ig for 5 days by PCR method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4056033 | A | Effect on FXR mRNA expression in C57BL/6 mouse duodenum at 100 mg/kg, ig for 5 days by PCR method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4056034 | A | Effect on FXR mRNA expression in C57BL/6 mouse jejunum at 100 mg/kg, ig for 5 days by PCR method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4056035 | A | Effect on FXR mRNA expression in C57BL/6 mouse liver at 100 mg/kg, ig for 5 days by PCR method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4056036 | A | Effect on FXR mRNA expression in C57BL/6 mouse kidney at 100 mg/kg, ig for 5 days by PCR method | Mus musculus | 1 | organism-based format | Scientific Literature |
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