| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4016908 | B | Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 2. | ALA4016909 | A | Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 3. | ALA4016910 | U | Selectivity ratio of IC50 for human CYP11B2 expressed in hamster V79MZ cells to IC50 for human CYP11B1 expressed in hamster V79MZ cells | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 4. | ALA4016911 | B | Inhibition of rat CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4016912 | B | Selectivity ratio of IC50 for rat CYP11B1 expressed in hamster V79MZ cells to IC50 for human CYP11B1 expressed in hamster V79MZ cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4016913 | A | Half life in human liver S9 fractions at 1 uM in presence of NADPH/UDPGA by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 7. | ALA4016914 | A | Half life in rat liver S9 fractions at 1 uM in presence of NADPH/UDPGA by LC-MS/MS analysis | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 8. | ALA4016915 | A | Inhibition of human CYP17A1 expressed in Escherichia coli membranes at 2 uM using [3H]-progesterone as substrate after 30 mins in presence of NADPH by HPLC analysis relative to control | Homo sapiens | 2 | cell membrane format | Scientific Literature | ||
| 9. | ALA4016916 | A | Inhibition of human placental microsomal CYP19A1 at 2 uM using [1beta-3H]-androstenedione as substrate after 20 mins in presence of NADPH by scintillation spectrometric method relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 10. | ALA4016917 | A | Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 11. | ALA4016918 | A | Inhibition of recombinant human CYP2B6 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 12. | ALA4016919 | A | Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 13. | ALA4016920 | A | Inhibition of recombinant human CYP2C19 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 14. | ALA4016921 | A | Inhibition of recombinant human CYP2D6 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA4016922 | A | Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 16. | ALA4016923 | A | Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 66 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4016924 | T | Mutagenicity in Salmonella typhimurium TA98 up to 100 uM by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature | ||
| 18. | ALA4016925 | T | Mutagenicity in Salmonella typhimurium TA98 up to 100 uM in presence of rat liver S9 fraction by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature | ||
| 19. | ALA4016926 | T | Mutagenicity in Salmonella typhimurium TA7001/7002/7003/7004/7005/7006 up to 100 uM by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature | ||
| 20. | ALA4016927 | T | Mutagenicity in Salmonella typhimurium TA7001/7002/7003/7004/7005/7006 up to 100 uM in presence of rat liver S9 fraction by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature |
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