| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4051302 | B | Agonist activity at human GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 2. | ALA4051303 | B | Agonist activity at human GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay relative to control | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 3. | ALA4051304 | F | Agonist activity at mouse GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium level after 5 mins by FLUO-4-AM dye-based FLIPR assay | Mus musculus | 30 | cell-based format | Scientific Literature | ||
| 4. | ALA4051305 | F | Agonist activity at mouse GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium level after 5 mins by FLUO-4-AM dye-based FLIPR assay relative to control | Mus musculus | 30 | cell-based format | Scientific Literature | ||
| 5. | ALA4051306 | P | Octanol-buffer partition coefficient, log D of the compound at pH 7.4 after 30 mins by LC-UV based shake-flask method | 19 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4051308 | T | Toxicity in mouse at 150 mg/kg, po after 2 hrs | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA4051311 | A | Drug uptake in mouse blood at 150 mg/kg, po after 2 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4051312 | T | Toxicity in mouse at 300 mg/kg, po after 1 hr | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4051313 | A | Drug uptake in mouse blood at 300 mg/kg, po after 1 hr | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4051314 | A | Drug uptake in mouse brain at 300 mg/kg, po after 1 hr | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4051315 | A | Protein binding in mouse plasma assessed as unbound fraction after 24 hrs by equilibrium dialysis | Mus musculus | 5 | cell-free format | Scientific Literature | ||
| 12. | ALA4051316 | A | Clearance in mouse at 2.5 mg/kg, iv after 24 hrs | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 13. | ALA4051318 | A | Volume of distribution at steady state in mouse at 2.5 mg/kg, iv after 24 hrs | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA4051320 | A | Cmax in mouse at 5 mg/kg administered through oral gavage after 24 hrs | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 15. | ALA4051321 | A | Oral bioavailability in mouse at 5 mg/kg after 24 hrs | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 16. | ALA4051322 | A | Ratio of drug level in mouse brain to blood at 5 mg/kg administered through oral gavage after 2 hrs | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 17. | ALA4051323 | A | Ratio of unbound drug level in mouse brain to blood at 5 mg/kg administered through oral gavage after 2 hrs | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 18. | ALA4051324 | A | Apparent permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA4051325 | A | Efflux ratio of permeability in MDCK2-MDR1 cells at 10 uM | Canis lupus familiaris | 4 | cell-based format | Scientific Literature | ||
| 20. | ALA4051330 | B | Inhibition of phosphodiesterase 4D (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!