| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4043761 | Functional | Neuroprotective activity against fibril amyloid beta (25 to 35)-induced cell death in Sprague-Dawley rat 5 day old neonatal primary cortical neurons assessed as cell death at maximum non toxic concentration pretreated for 2 hrs followed by 10 uM fibril amyloid beta (25 to 35) addition measured after 48 hrs by MTT assay (Rvb = 39.20 +/- 0.88%) | Rattus norvegicus | 36 | ALA4043092 | cell-based format | Scientific Literature | |
| 2. | ALA4043762 | Functional | Neuroprotective activity against glutamate-induced cell death in Sprague-Dawley rat 10 days old neonatal primary cortical neurons assessed as cell death at maximum non toxic concentration pretreated for 2 hrs followed by 30 uM glutamate addition measured after 24 hrs by MTT assay (Rvb = 41.22 +/- 3.40%) | Rattus norvegicus | 36 | ALA4043092 | cell-based format | Scientific Literature | |
| 3. | ALA4043771 | Functional | Anti-inflammatory activity in Sprague-Dawley rat primary mixed glial cells assessed as inhibition of LPS-induced NO production at 50 uM pretreated for 2 hrs followed by LPS addition measured after 48 hrs by Griess assay (Rvb = 100%) | Rattus norvegicus | 36 | ALA4043092 | cell-based format | Scientific Literature |
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