#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4009734	Physicochemical	Permeability, logPe of the compound after 4 hrs by PAMPA		4	ALA4007443	small-molecule physicochemical format	Scientific Literature
2.	ALA4009735	Binding	Inhibition of mouse glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 mins followed by enzyme addition by pGAPase coupled fluorometry	Mus musculus	2	ALA4007443	single protein format	Scientific Literature
3.	ALA4009736	Binding	Inhibition of human glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 mins followed by enzyme addition by pGAPase coupled fluorometry	Homo sapiens	53	ALA4007443	single protein format	Scientific Literature
4.	ALA4009737	Binding	Inhibition of iso glutaminyl cyclase (unknown origin)	Homo sapiens	1	ALA4007443	single protein format	Scientific Literature
5.	ALA4009738	Binding	Ratio of IC50 for iso glutaminyl cyclase (unknown origin) to IC50 for human glutaminyl cyclase	Homo sapiens	1	ALA4007443	assay format	Scientific Literature
6.	ALA4009739	ADME	Cytotoxicity against mouse HT22 cells assessed as cell viability at 10 uM after 18 hrs by MTT assay	Mus musculus	9	ALA4007443	cell-based format	Scientific Literature
7.	ALA4009740	Functional	Antialzheimer activity in human amyloid beta (3 to 40) induced acute ICR mouse Alzheimer's disease mouse model assessed as inhibition of amyloid beta (N3pE to 40) formation in brain at 10 mM, icv by sandwich ELISA	Mus musculus	9	ALA4007443	assay format	Scientific Literature
8.	ALA4009741	Functional	Antialzheimer activity in human amyloid beta (3 to 40) induced acute ICR mouse Alzheimer's disease mouse model assessed as inhibition of amyloid beta (N3pE to 40) formation in brain at 25 mg/kg, ip by sandwich ELISA	Mus musculus	4	ALA4007443	organism-based format	Scientific Literature
9.	ALA4009742	ADME	Stability in mouse liver microsomes assessed as compound remaining after 30 mins	Mus musculus	1	ALA4007443	assay format	Scientific Literature
10.	ALA4009743	Functional	Invivo inhibition of glutaminyl cyclase in APP/PS1 transgenic Alzheimer's disease mouse model assessed as reduction in amyloid beta (N3pE to 40) levels in brain administered via deep cortical/hippocampus brain infusion via miniosmotic pumps for 3 weeks	Mus musculus	1	ALA4007443	assay format	Scientific Literature
11.	ALA4009744	Functional	Invivo inhibition of glutaminyl cyclase in APP/PS1 transgenic Alzheimer's disease mouse model assessed as reduction in total amyloid beta levels administered via deep cortical/hippocampus brain infusion via miniosmotic pumps for 3 weeks	Mus musculus	1	ALA4007443	assay format	Scientific Literature
12.	ALA4009745	Functional	Cognition enhancement activity in 5XFAD Alzheimer's disease mouse model assessed as reduction in escape latency in hidden platform training over repeated sessions administered intraperitoneally starting from 19 to 34 weeks of age by Morris water maze test	Mus musculus	1	ALA4007443	assay format	Scientific Literature
13.	ALA4009746	Functional	Cognition enhancement activity in 5XFAD Alzheimer's disease mouse model assessed as increase in duration of time spent in target quadrant administered intraperitoneally starting from 19 to 34 weeks of age by Morris water maze test	Mus musculus	1	ALA4007443	assay format	Scientific Literature
14.	ALA4009747	Toxicity	Toxicity in APP/PS1 transgenic Alzheimer's disease mouse model administered via icv for 3 weeks	Mus musculus	1	ALA4007443	assay format	Scientific Literature
15.	ALA4376103	Binding	Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect cells using H-Gln-AMC hydrobromide as substrate measured in presence of pGAPase by fluorometric assay	Homo sapiens	68	ALA4373720	cell-based format	Scientific Literature
16.	ALA5035499	Binding	Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry	Homo sapiens	92	ALA5034025	single protein format	Scientific Literature