#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4009734	P	Permeability, logPe of the compound after 4 hrs by PAMPA		4		small-molecule physicochemical format	Scientific Literature
2.	ALA4009735	B	Inhibition of mouse glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 mins followed by enzyme addition by pGAPase coupled fluorometry	Mus musculus	2		single protein format	Scientific Literature
3.	ALA4009736	B	Inhibition of human glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 mins followed by enzyme addition by pGAPase coupled fluorometry	Homo sapiens	53		single protein format	Scientific Literature
4.	ALA4009737	B	Inhibition of iso glutaminyl cyclase (unknown origin)	Homo sapiens	1		single protein format	Scientific Literature
5.	ALA4009738	B	Ratio of IC50 for iso glutaminyl cyclase (unknown origin) to IC50 for human glutaminyl cyclase	Homo sapiens	1		assay format	Scientific Literature
6.	ALA4009739	A	Cytotoxicity against mouse HT22 cells assessed as cell viability at 10 uM after 18 hrs by MTT assay	Mus musculus	9		cell-based format	Scientific Literature
7.	ALA4009740	F	Antialzheimer activity in human amyloid beta (3 to 40) induced acute ICR mouse Alzheimer's disease mouse model assessed as inhibition of amyloid beta (N3pE to 40) formation in brain at 10 mM, icv by sandwich ELISA	Mus musculus	9		assay format	Scientific Literature
8.	ALA4009741	F	Antialzheimer activity in human amyloid beta (3 to 40) induced acute ICR mouse Alzheimer's disease mouse model assessed as inhibition of amyloid beta (N3pE to 40) formation in brain at 25 mg/kg, ip by sandwich ELISA	Mus musculus	4		organism-based format	Scientific Literature
9.	ALA4009742	A	Stability in mouse liver microsomes assessed as compound remaining after 30 mins	Mus musculus	1		assay format	Scientific Literature
10.	ALA4009743	F	Invivo inhibition of glutaminyl cyclase in APP/PS1 transgenic Alzheimer's disease mouse model assessed as reduction in amyloid beta (N3pE to 40) levels in brain administered via deep cortical/hippocampus brain infusion via miniosmotic pumps for 3 weeks	Mus musculus	1		assay format	Scientific Literature
11.	ALA4009744	F	Invivo inhibition of glutaminyl cyclase in APP/PS1 transgenic Alzheimer's disease mouse model assessed as reduction in total amyloid beta levels administered via deep cortical/hippocampus brain infusion via miniosmotic pumps for 3 weeks	Mus musculus	1		assay format	Scientific Literature
12.	ALA4009745	F	Cognition enhancement activity in 5XFAD Alzheimer's disease mouse model assessed as reduction in escape latency in hidden platform training over repeated sessions administered intraperitoneally starting from 19 to 34 weeks of age by Morris water maze test	Mus musculus	1		assay format	Scientific Literature
13.	ALA4009746	F	Cognition enhancement activity in 5XFAD Alzheimer's disease mouse model assessed as increase in duration of time spent in target quadrant administered intraperitoneally starting from 19 to 34 weeks of age by Morris water maze test	Mus musculus	1		assay format	Scientific Literature
14.	ALA4009747	T	Toxicity in APP/PS1 transgenic Alzheimer's disease mouse model administered via icv for 3 weeks	Mus musculus	1		assay format	Scientific Literature
15.	ALA4376103	B	Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect cells using H-Gln-AMC hydrobromide as substrate measured in presence of pGAPase by fluorometric assay	Homo sapiens	68		cell-based format	Scientific Literature
16.	ALA5035499	B	Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry	Homo sapiens	92		single protein format	Scientific Literature