| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4043569 | A | Half life in human liver microsomes at 3 uM up to 45 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 17 | ALA4043075 | assay format | Scientific Literature | |
| 2. | ALA4043570 | A | Half life in Sprague-Dawley rat liver microsomes at 3 uM up to 45 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 17 | ALA4043075 | assay format | Scientific Literature | |
| 3. | ALA4043571 | A | Drug metabolism assessed as human CYP2D6-mediated compound degradation by measuring half life at 5 uM up to 45 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 6 | ALA4043075 | single protein format | Scientific Literature | |
| 4. | ALA4043572 | B | Inhibition of Wistar rat heart mitochondrial CPT-1 assessed as reduction in conversion of palmitoyl CoA and L-carnitine into palmitoylcarnitine preincubated for 3 mins followed by L-carnitine and palmitoyl CoA addition measured for 3.5 mins by spectrophotometric analysis | Rattus norvegicus | 11 | ALA4043075 | single protein format | Scientific Literature | |
| 5. | ALA4043598 | P | Stability of the compound in pH 7.4 PBS buffer at 37 degC after 1 hr | 15 | ALA4043075 | small-molecule physicochemical format | Scientific Literature |
The page will load shortly, Thanks for your patience!