# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4013915 | B | Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed by H2O2 addition measured after 5 mins | Homo sapiens | 33 | ALA4011652 | single protein format | Scientific Literature | |
2. | ALA4013917 | B | Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidation by measuring residual activity at 5 uM in absence of H2O2 incubated for 5 mins followed by 100 fold enzyme dilution relative to control | Homo sapiens | 9 | ALA4011652 | single protein format | Scientific Literature | |
3. | ALA4013918 | B | Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidation by measuring residual activity at 5 uM in presence of H2O2 incubated for 5 mins followed by 100 fold enzyme dilution relative to control | Homo sapiens | 9 | ALA4011652 | single protein format | Scientific Literature | |
4. | ALA4013919 | B | Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidation by measuring residual activity at 5 uM in presence of H2O2 and NaCl incubated for 5 mins followed by 100 fold enzyme dilution relative to control | Homo sapiens | 9 | ALA4011652 | single protein format | Scientific Literature | |
5. | ALA4013920 | B | Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISA | Homo sapiens | 9 | ALA4011652 | single protein format | Scientific Literature | |
6. | ALA4013924 | B | Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | Bos taurus | 12 | ALA4011652 | single protein format | Scientific Literature | |
7. | ALA4013941 | A | Cytotoxicity against NHDF assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4011652 | cell-based format | Scientific Literature | |
8. | ALA4013945 | B | Selectivity ratio of IC50 for bovine milk LPO to IC50 for recombinant MPO (unknown origin) | 12 | ALA4011652 | assay format | Scientific Literature |