| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4034740 | F | Decrease in CDC25C protein expression level in human A431 cell extract at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 2. | ALA4034741 | B | Inhibition of recombinant human full length GST-tagged CDC25A expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as substrate after 2 hrs by fluorimetric analysis | Homo sapiens | 19 | ALA4033647 | assay format | Scientific Literature | |
| 3. | ALA4034742 | B | Inhibition of recombinant human full length GST-tagged CDC25C expressed in Escherichia coli BL21-DE3 pLysS using 3-O-methylfluorescein phosphate as substrate after 2 hrs by fluorimetric analysis | Homo sapiens | 19 | ALA4033647 | assay format | Scientific Literature | |
| 4. | ALA4034743 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 19 | ALA4033647 | cell-based format | Scientific Literature | |
| 5. | ALA4034744 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 19 | ALA4033647 | cell-based format | Scientific Literature | |
| 6. | ALA4034745 | F | Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 19 | ALA4033647 | cell-based format | Scientific Literature | |
| 7. | ALA4034746 | F | Cytotoxicity against human U373n cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 19 | ALA4033647 | cell-based format | Scientific Literature | |
| 8. | ALA4034747 | F | Cytotoxicity against human Hs683 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 19 | ALA4033647 | cell-based format | Scientific Literature | |
| 9. | ALA4034748 | F | Cytotoxicity against human SK-MEL-28 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 19 | ALA4033647 | cell-based format | Scientific Literature | |
| 10. | ALA4034753 | F | Cytotoxicity against human A431 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 11. | ALA4034755 | F | Cell cycle arrest in human A431 cells assessed as accumulation at G1 phase at 10 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 53.04%) | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 12. | ALA4034756 | F | Cell cycle arrest in human A431 cells assessed as accumulation at G1 phase at 50 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 53.04%) | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 13. | ALA4034757 | F | Cell cycle arrest in human A431 cells assessed as accumulation at S phase at 10 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 17.33%) | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 14. | ALA4034758 | F | Cell cycle arrest in human A431 cells assessed as accumulation at S phase at 50 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 17.33%) | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 15. | ALA4034759 | F | Cell cycle arrest in human A431 cells assessed as accumulation at G2/M phase at 10 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 26.23%) | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 16. | ALA4034760 | F | Cell cycle arrest in human A431 cells assessed as accumulation at G2/M phase at 50 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 26.23%) | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 17. | ALA4034761 | F | Cell cycle arrest in human A431 cells assessed as accumulation at subG1 phase at 10 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 3.40%) | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 18. | ALA4034762 | F | Cell cycle arrest in human A431 cells assessed as accumulation at subG1 phase at 50 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 3.40%) | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 19. | ALA4034763 | F | Effect on CDC25C splice variant protein expression in human A431 cell extract at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA4033647 | cell-based format | Scientific Literature | |
| 20. | ALA4034764 | B | Inhibition of CDC25C in human A431 cells assessed as increase in phosphorylation of CDK1 at Thr14/Tyr15 residues at 50 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4033647 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!