# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4057803 | Binding | Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation for 3.5 hrs by ELISA | Homo sapiens | 18 | ALA4052764 | single protein format | Scientific Literature | |
2. | ALA4057805 | ADME | AUC in rat assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione level at 10 mg/kg, po by HPLC/MS analysis | Rattus norvegicus | 17 | ALA4052764 | organism-based format | Scientific Literature | |
3. | ALA4057809 | ADME | AUC in rat assessed as rapid AUC measured from dosing of parent at 10 mg/kg, po by HPLC/MS analysis | Rattus norvegicus | 9 | ALA4052764 | organism-based format | Scientific Literature |