| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4051431 | Binding | Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured after 1 hr by RapidFire high-throughput mass spectrometric analysis | Homo sapiens | 35 | ALA4049435 | assay format | Scientific Literature | |
| 2. | ALA4051432 | Binding | Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysis | Homo sapiens | 33 | ALA4049435 | cell-based format | Scientific Literature | |
| 3. | ALA4051434 | ADME | Binding affinity to human serum albumin by HPLC analysis | Homo sapiens | 28 | ALA4049435 | single protein format | Scientific Literature | |
| 4. | ALA4051435 | Physicochemical | Permeability of the compound by PAMPA | 24 | ALA4049435 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA4051436 | Physicochemical | Lipophilicity, log D of the compound at pH 7.4 by RP-HPLC analysis | 33 | ALA4049435 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4051437 | ADME | Protein binding in human plasma | Homo sapiens | 33 | ALA4049435 | cell-free format | Scientific Literature |
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