# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4027162 | ADME | Cytotoxicity against HEK293 cells assessed as cell viability at 50 uM after 24 hrs by Alamar blue assay relative to control | Homo sapiens | 33 | ALA4024766 | cell-based format | Scientific Literature | |
2. | ALA4027165 | Unassigned | Selectivity index, ratio of IC50 for recombinant human full length HDAC6 to IC50 for recombinant human full length C-terminal His-tagged HDAC8 | Homo sapiens | 11 | ALA4024766 | assay format | Scientific Literature | |
3. | ALA4027167 | ADME | Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimetric analysis | Homo sapiens | 31 | ALA4024766 | cell-based format | Scientific Literature | |
4. | ALA4027168 | ADME | Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells at 1 uM using fluorogenic ZMAL as substrate after 90 mins by fluorimetric analysis | Homo sapiens | 20 | ALA4024766 | cell-based format | Scientific Literature | |
5. | ALA4027169 | ADME | Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells at 10 uM using fluorogenic ZMAL as substrate after 90 mins by fluorimetric analysis | Homo sapiens | 19 | ALA4024766 | cell-based format | Scientific Literature | |
6. | ALA4027170 | Unassigned | Selectivity index, ratio of IC50 for recombinant human full length C-terminal FLAG-tagged HDAC1 to IC50 for recombinant human full length C-terminal His-tagged HDAC8 | Homo sapiens | 11 | ALA4024766 | assay format | Scientific Literature | |
7. | ALA4027173 | ADME | Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells at 10 uM using fluorogenic ZMAL as substrate after 90 mins by fluorimetric analysis | Homo sapiens | 19 | ALA4024766 | cell-based format | Scientific Literature | |
8. | ALA4027177 | ADME | Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimetric analysis | Homo sapiens | 31 | ALA4024766 | cell-based format | Scientific Literature | |
9. | ALA4027179 | ADME | Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells at 1 uM using fluorogenic ZMAL as substrate after 90 mins by fluorimetric analysis | Homo sapiens | 19 | ALA4024766 | cell-based format | Scientific Literature | |
10. | ALA4027180 | Binding | Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate after 90 mins by fluorimetric analysis | Homo sapiens | 31 | ALA4024766 | assay format | Scientific Literature |