| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4021806 | B | Inhibition of Candida albicans CDR1 expressed in Saccharomyces cerevisiae AD assessed as reduction in nile red dye efflux at 70 uM after 30 mins by flow cytometry relative to control | Candida albicans | 19 | assay format | Scientific Literature | ||
| 2. | ALA4021807 | B | Inhibition of Candida albicans MDR1 expressed in Saccharomyces cerevisiae AD assessed as reduction in nile red dye efflux at 70 uM after 30 mins by flow cytometry relative to control | Candida albicans | 19 | assay format | Scientific Literature | ||
| 3. | ALA4021808 | F | Antifungal activity against Saccharomyces cerevisiae AD1-8u(-) after 48 hrs | Saccharomyces cerevisiae | 19 | assay format | Scientific Literature | ||
| 4. | ALA4021809 | F | Antifungal activity against Saccharomyces cerevisiae AD over-expressing Candida albicans CDR1 after 48 hrs | Saccharomyces cerevisiae | 19 | assay format | Scientific Literature | ||
| 5. | ALA4021810 | F | Antifungal activity against Saccharomyces cerevisiae AD over-expressing Candida albicans MDR1 after 48 hrs | Saccharomyces cerevisiae | 19 | assay format | Scientific Literature | ||
| 6. | ALA4021811 | F | Resistance index, ratio of MIC80 for Saccharomyces cerevisiae AD over-expressing Candida albicans CDR1 to MIC80 for Saccharomyces cerevisiae AD1-8u(-) | Saccharomyces cerevisiae | 19 | assay format | Scientific Literature | ||
| 7. | ALA4021812 | F | Resistance index, ratio of MIC80 for Saccharomyces cerevisiae AD over-expressing Candida albicans MDR1 to MIC80 for Saccharomyces cerevisiae AD1-8u(-) | Saccharomyces cerevisiae | 19 | assay format | Scientific Literature | ||
| 8. | ALA4021813 | F | Synergistic antifungal activity against Saccharomyces cerevisiae AD1-8u(-) assessed as ratio of compound MIC80 in combinantion with fluconazole to compound alone MIC80 by checkerboard method | Saccharomyces cerevisiae | 19 | assay format | Scientific Literature | ||
| 9. | ALA4021814 | F | Potentiation of fluconazole-induced antifungal activity against Saccharomyces cerevisiae AD1-8u(-) by checkerboard method | Saccharomyces cerevisiae | 19 | assay format | Scientific Literature | ||
| 10. | ALA4021815 | B | Inhibition of Candida albicans CDR1 expressed in Saccharomyces cerevisiae AD assessed as ratio of compound MIC80 in combinantion with fluconazole to compound alone MIC80 for Saccharomyces cerevisiae AD by checkerboard method | Candida albicans | 19 | assay format | Scientific Literature | ||
| 11. | ALA4021816 | B | Inhibition of Candida albicans CDR1 expressed in Saccharomyces cerevisiae AD assessed as potentiation of fluconazole-induced antifungal activity against Saccharomyces cerevisiae AD by checkerboard method | Candida albicans | 19 | assay format | Scientific Literature | ||
| 12. | ALA4021817 | B | Inhibition of Candida albicans MDR1 expressed in Saccharomyces cerevisiae AD assessed as ratio of compound MIC80 in combinantion with fluconazole to compound alone MIC80 for Saccharomyces cerevisiae AD by checkerboard method | Candida albicans | 19 | assay format | Scientific Literature | ||
| 13. | ALA4021818 | B | Inhibition of Candida albicans MDR1 expressed in Saccharomyces cerevisiae AD assessed as potentiation of fluconazole-induced antifungal activity against Saccharomyces cerevisiae AD by checkerboard method | Candida albicans | 19 | assay format | Scientific Literature | ||
| 14. | ALA4021820 | P | Lipophilicity, log P of the compound | 19 | small-molecule physicochemical format | Scientific Literature |
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