# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4004097 | ADME | Cytotoxicity in HEK293 cells assessed as cell viability at 100 uM measured after 20 to 24 hrs by Cell-Titer Blue fluorescence assay | Homo sapiens | 23 | ALA4002619 | cell-based format | Scientific Literature | |
2. | ALA4004099 | ADME | Inhibition of human SGLT1 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose addition in presence of sodium buffer measured after 1 hr by resazurin dye based fluorescence assay | Homo sapiens | 24 | ALA4002619 | cell-based format | Scientific Literature | |
3. | ALA4004100 | Binding | Inhibition of human SGLT2 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose addition in presence of sodium buffer measured after 1 hr by resazurin dye based fluorescence assay | Homo sapiens | 24 | ALA4002619 | cell-based format | Scientific Literature | |
4. | ALA4004101 | Unassigned | Selectivity ratio of IC50 for human SGLT1 to IC50 for human SGLT2 | Homo sapiens | 9 | ALA4002619 | assay format | Scientific Literature | |
5. | ALA4004102 | Binding | Inhibition of human SGLT2 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake at 100 uM pretreated for 10 mins followed by 2-deoxyglucose addition in presence of sodium buffer measured after 1 hr by resazurin dye based fluorescence assay | Homo sapiens | 24 | ALA4002619 | cell-based format | Scientific Literature | |
6. | ALA4004103 | ADME | Inhibition of human SGLT1 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake at 100 uM pretreated for 10 mins followed by 2-deoxyglucose addition in presence of sodium buffer measured after 1 hr by resazurin dye based fluorescence assay | Homo sapiens | 24 | ALA4002619 | cell-based format | Scientific Literature | |
7. | ALA4004106 | ADME | Inhibition of GLUT in HEK293 cells assessed as reduction in 2-deoxyglucose uptake at 100 uM pretreated for 10 mins followed by 2-deoxyglucose addition in presence of choline buffer measured after 1 hr by resazurin dye based fluorescence assay | Homo sapiens | 22 | ALA4002619 | cell-based format | Scientific Literature |