| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4055896 | B | Inhibition of acid-induced wild type transthyretin (unknown origin) aggregation expressed in Escherichia coli pre-incubated for 30 mins before acid addition and further incubated for 72 hrs at 37 degC under dark conditions by UV-Vis spectrophotometry | Homo sapiens | 289 | assay format | Scientific Literature | ||
| 2. | ALA4055897 | B | Binding affinity to transthyretin in human blood plasma assessed as plasma binding selectivity by measuring stoichiometry of small molecule bound to TTR incubated for 24 hrs at 37 degC by RP-HPLC | Homo sapiens | 288 | single protein format | Scientific Literature | ||
| 3. | ALA4667325 | B | Activation of human TREK2 at 30 uM by thallium flux mobilization assay relative to control | Homo sapiens | 33 | single protein format | Scientific Literature | ||
| 4. | ALA4667328 | B | Activation of human TREK1 at 30 uM by thallium flux mobilization assay relative to control | Homo sapiens | 33 | single protein format | Scientific Literature |
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