| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4017397 | B | Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using varying levels of fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by Lineweaver-Burk plot analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA4017398 | B | Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA4017399 | B | Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA4017400 | B | Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA4017401 | B | Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 6. | ALA4017402 | B | Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 7. | ALA4017403 | B | Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 8. | ALA4017404 | B | Selectivity ratio of IC50 for recombinant human MMP1 expressed in mouse NSO cells to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4017405 | B | Selectivity ratio of IC50 for recombinant human MMP2 expressed in mouse NSO cells to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4017406 | B | Selectivity ratio of IC50 for MMP8 (unknown origin) to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4017407 | B | Selectivity ratio of IC50 for MMP9 (unknown origin) to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4017408 | B | Selectivity ratio of IC50 for recombinant human MMP14 to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4017411 | B | Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen at 20 uM after 24 hrs by SDS-PAGE analysis relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 14. | ALA5217287 | B | Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescence microplate reader assay | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 15. | ALA5217288 | B | Inhibition of Collagen-II-alpha 1 (unknown origin) at 20 uM incubated for 22 hrs by Coomassie blue staining based SDS-PAGE analysis | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 16. | ALA5217289 | B | Inhibition of MMP-1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA5217292 | B | Inhibition of MMP-1 (unknown origin) at 5 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 18. | ALA5217293 | B | Inhibition of MMP-2 (unknown origin) using fTHP-15(FAM) as substrate at 5 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 19. | ALA5217294 | B | Inhibition of MMP-8 (unknown origin) using fTHP-15(FAM) as substrate at 5 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 20. | ALA5217295 | B | Inhibition of MMP-9 (unknown origin) using fTHP-15(FAM) as substrate at 5 uM | Homo sapiens | 5 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!