# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3995517 | F | Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
2. | ALA3995519 | F | Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
3. | ALA3995521 | F | Agonist activity at mouse GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
4. | ALA3995522 | F | Agonist activity at GPR39 (unknown origin) expressed in COS7 cells co-expressing Galphas assessed as increase in intracellular cAMP level measured after 30 mins by chemiluminescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA3995523 | F | Agonist activity at GPR39 (unknown origin) expressed in COS7 cells co-expressing Galphas assessed as increase in intracellular cAMP level in presence of 3 uM Zn2+ measured after 30 mins by chemiluminescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA3995524 | F | Agonist activity at human ghrelin receptor (117 residues) assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
7. | ALA3995525 | F | Agonist activity at human motilin receptor (412 residues) assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA3995526 | F | Agonist activity at human NMU2 receptor assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA3995531 | F | Agonist activity at full length human CCR1 assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA3995532 | F | Agonist activity at full length rhesus monkey CCR5 assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay | Macaca mulatta | 2 | single protein format | Scientific Literature | ||
11. | ALA3995533 | F | Agonist activity at human ghrelin receptor (117 residues) assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
12. | ALA3995534 | F | Agonist activity at human motilin receptor (412 residues) assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
13. | ALA3995535 | F | Agonist activity at human NMU2 receptor assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
14. | ALA3995536 | F | Agonist activity at full length human CCR1 assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
15. | ALA3995537 | F | Agonist activity at full length monkey CCR5 assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Macaca mulatta | 2 | single protein format | Scientific Literature | ||
16. | ALA3995540 | B | Agonist activity at GPR39 in primary gastric mucosal cells isolated from C57BL/6 mouse assessed as inhibition of isoproterenol-induced ghrelin secretion at 1 uM in presence of 10 uM of Zn2+ measured after 4 hrs by ELISA relative to basal level | Mus musculus | 2 | assay format | Scientific Literature | ||
17. | ALA3995541 | B | Agonist activity at GPR39 in primary gastric mucosal cells isolated from C57BL/6 mouse assessed as inhibition of isoproterenol-induced ghrelin secretion at 1 uM in presence of 10 uM of Zn2+ and somatostatin receptor antagonist BIM-23627 measured after 4 hrs by ELISA | Mus musculus | 2 | assay format | Scientific Literature | ||
18. | ALA3995542 | F | Increase in CGRP-induced somatostatin release in primary gastric mucosal cells isolated from GPR39 deficient C57BL/6 mouse at 1 uM in presence of 10 uM of Zn2+ measured after 4 hrs by radioimmunoassay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
19. | ALA3995543 | F | Induction of CGRP-induced somatostatin release in primary gastric mucosal cells isolated from GPR39 deficient C57BL/6 mouse at 1 uM in presence of 10 uM of Zn2+ measured after 4 hrs by radioimmunoassay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
20. | ALA3995544 | F | Agonist activity at GPR39 in primary gastric mucosal cells isolated from C57BL/6 mouse assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay | Mus musculus | 2 | assay format | Scientific Literature |