# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4035077 | Binding | Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotometry based SEAP reporter gene assay | Homo sapiens | 17 | ALA4033660 | cell-based format | Scientific Literature | |
2. | ALA4035080 | Binding | Antagonist activity at human TLR7 expressed in HEK293 cells assessed as inhibition of CL264-induced NF-kappaB activation after 24 hrs by spectrophotometry based SEAP reporter gene assay | Homo sapiens | 9 | ALA4033660 | cell-based format | Scientific Literature | |
3. | ALA4035081 | Binding | Selectivity ratio of IC50 for human TLR7 expressed in HEK293 cells to IC50 for human TLR9 expressed in HEK293 cells | Homo sapiens | 9 | ALA4033660 | cell-based format | Scientific Literature | |
4. | ALA4035082 | Binding | Antagonist activity at TLR9 in human PBMC assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA | Homo sapiens | 5 | ALA4033660 | single protein format | Scientific Literature | |
5. | ALA4035083 | Binding | Antagonist activity at TLR9 in human plasmacytoid dendritic cells assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA | Homo sapiens | 5 | ALA4033660 | assay format | Scientific Literature |