| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4022773 | B | Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substrate assessed as decrease in IMP levels after 1 hr by mass spectrometric method | Homo sapiens | 19 | ALA4020815 | assay format | Scientific Literature | |
| 2. | ALA4022774 | B | Inhibition of AICARFT in human NCI-H460 cells assessed as increase in ZMP levels using low folate media after 16 hrs by LC-MS method | Homo sapiens | 18 | ALA4020815 | cell-based format | Scientific Literature | |
| 3. | ALA4022780 | A | Permeability across apical to basolateral side in MDCK cells at 20 uM | Canis lupus familiaris | 14 | ALA4020815 | cell-based format | Scientific Literature | |
| 4. | ALA4022784 | A | Plasma concentration in CD-1 mouse at 10 mg/kg, po after 1 hr by LC-MS/MS method | Mus musculus | 12 | ALA4020815 | organism-based format | Scientific Literature | |
| 5. | ALA4022785 | A | Fraction unbound in CD-1 mouse plasma | Mus musculus | 12 | ALA4020815 | cell-free format | Scientific Literature |
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