# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4046295 | B | Inhibition of Trypanosoma brucei AdoMetDC pre-incubated for 30 mins before AdoMet substrate addition by RapidFire-mass spectrometry | Trypanosoma brucei | 24 | assay format | Scientific Literature | ||
2. | ALA4046301 | B | Inhibition of Trypanosoma brucei AdoMetDC at 50 uM without pre-incubation for 30 mins before AdoMet substrate addition by RapidFire-mass spectrometry | Trypanosoma brucei | 5 | assay format | Scientific Literature | ||
3. | ALA4046302 | F | Antitrypanosomal activity against Trypanosoma brucei Lister 427 bloodstream forms assessed as inhibition of parasite growth incubated for 48 hrs by ATP-bioluminescence cell viability assay | Trypanosoma brucei | 23 | assay format | Scientific Literature | ||
4. | ALA4046304 | A | Apparent permeability in MDCK2-MDR1 cells at 3 uM incubated for 1 hr in presence of P-glycoprotein inhibitor GF120918 by LC/MS/MS method | Canis lupus familiaris | 26 | cell-based format | Scientific Literature | ||
5. | ALA4046305 | A | Half life in human pooled liver microsomes at 1 uM in presence of NADPH by LC/MS/MS method | Homo sapiens | 27 | assay format | Scientific Literature | ||
6. | ALA4046306 | A | Half life in mouse pooled liver microsomes at 1 uM in presence of NADPH by LC/MS/MS method | Mus musculus | 27 | assay format | Scientific Literature |