| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4011563 | B | Inhibition of recombinant Top1 (unknown origin) assessed as increase in [32P]-DNA breaks at 0.1 to 100 uM after 20 mins by PAGE analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 2. | ALA4011566 | B | Inhibition of recombinant Tdp1 (unknown origin) assessed as decrease in hydrolysis of phosphodiester linkage between tyrosine residue and the 3' end of 5'-[32P]-DNA after 15 mins by PAGE analysis | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 3. | ALA4011567 | B | Inhibition of recombinant human Tdp2 assessed as decrease in alpha 32P-cordycepin-3'-labeled DNA breaks after 15 mins by PAGE analysis | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 4. | ALA4011568 | F | Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4011569 | F | Cytotoxicity against human SF539 cells after 48 hrs by SRB assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 6. | ALA4011570 | F | Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 7. | ALA4011571 | F | Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 8. | ALA4011572 | F | Cytotoxicity against human SN12C cells after 48 hrs by SRB assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 9. | ALA4011573 | F | Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 10. | ALA4011574 | F | Induction of DNA damage in human CCRF-CEM cells assessed as formation of gamma-H2AX foci at 100 to 1000 nM after 2 hrs by DAPI staining-based confocal microscopy | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA4011575 | A | Induction of DNA damage in human PBMC assessed as formation of gamma-H2AX foci at 100 to 1000 nM after 2 hrs by DAPI staining-based confocal microscopy | Homo sapiens | 5 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!