# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4050695 | Binding | Inhibition of replicating Mycobacterium tuberculosis H37Rv NDH assessed as cell growth inhibition after 7 days by MABA method | Mycobacterium tuberculosis H37Rv | 71 | ALA4049411 | assay format | Scientific Literature | |
2. | ALA4050697 | ADME | Cytotoxicity against human HepG2 cells after 24 hrs in presence of glucose by MTT assay | Homo sapiens | 11 | ALA4049411 | cell-based format | Scientific Literature | |
3. | ALA4050698 | Unassigned | Therapeutic index, ratio of cytotoxicity for human HepG2 cells to IC50 for replicating Mycobacterium tuberculosis H37Rv NDH | 11 | ALA4049411 | cell-based format | Scientific Literature | ||
4. | ALA4050699 | ADME | Metabolic stability in human liver microsomes assessed as half life for metabolic turnover at 0.1 to 10 uM preincubated for 60 mins in presence of NADPH measured up to 60 mins by mass spectroscopic analysis | Homo sapiens | 11 | ALA4049411 | assay format | Scientific Literature | |
5. | ALA4050700 | ADME | Metabolic stability in mouse liver microsomes assessed as half life for metabolic turnover at 0.1 to 10 uM preincubated for 60 mins in presence of NADPH measured up to 60 mins by mass spectroscopic analysis | Mus musculus | 11 | ALA4049411 | assay format | Scientific Literature | |
6. | ALA4050701 | ADME | Metabolic stability in rat liver microsomes assessed as half life for metabolic turnover at 0.1 to 10 uM preincubated for 60 mins in presence of NADPH measured up to 60 mins by mass spectroscopic analysis | Rattus norvegicus | 11 | ALA4049411 | assay format | Scientific Literature |