# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3993624 | B | Inhibition of recombinant human CA1 preincubated for 15 mins by stopped-flow CO2 hydration assay | Homo sapiens | 17 | ALA3992527 | single protein format | Scientific Literature | |
2. | ALA3993625 | B | Inhibition of recombinant human CA2 preincubated for 15 mins by stopped-flow CO2 hydration assay | Homo sapiens | 17 | ALA3992527 | single protein format | Scientific Literature | |
3. | ALA3993626 | B | Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assay | Homo sapiens | 17 | ALA3992527 | single protein format | Scientific Literature | |
4. | ALA3993627 | B | Inhibition of recombinant human CA7 preincubated for 15 mins by stopped-flow CO2 hydration assay | Homo sapiens | 17 | ALA3992527 | single protein format | Scientific Literature | |
5. | ALA3993628 | B | Inhibition of recombinant human CA9 catalytic domain preincubated for 15 mins by stopped-flow CO2 hydration assay | Homo sapiens | 17 | ALA3992527 | single protein format | Scientific Literature | |
6. | ALA3993629 | B | Inhibition of recombinant human CA12 preincubated for 15 mins by stopped-flow CO2 hydration assay | Homo sapiens | 17 | ALA3992527 | single protein format | Scientific Literature | |
7. | ALA4403677 | A | Inhibition of COX1 in human platelet rich plasma in assessed as inhibition of ADP-induced platelet aggregation at 10 uM incubated for 5 mins by turbidimetry based Born's method relative to control | Homo sapiens | 11 | ALA4402543 | cell-free format | Scientific Literature | |
8. | ALA4403678 | B | Inhibition of COX2 in mouse RAW264.7 cells assessed as reduction in LPS-induced inflammation by measuring PGE2 level at 1 uM treated 1 hr after LPS stimulation and measured after 18 hrs by ELISA (Rvb = (2437 +/- 93.17 pg/mL) | Mus musculus | 12 | ALA4402543 | cell-based format | Scientific Literature | |
9. | ALA4403679 | B | Inhibition of COX2 in mouse RAW264.7 cells assessed as reduction in LPS-induced inflammation by measuring PGE2 level at 100 uM treated 1 hr after LPS stimulation and measured after 18 hrs by ELISA (Rvb = (2437 +/- 93.17 pg/mL) | Mus musculus | 11 | ALA4402543 | cell-based format | Scientific Literature | |
10. | ALA4403708 | A | Half life in human plasma by LC-MS/MS analysis | Homo sapiens | 28 | ALA4402543 | cell-free format | Scientific Literature | |
11. | ALA4403709 | A | Half life in Sprague-Dawley rat plasma by LC-MS/MS analysis | Rattus norvegicus | 28 | ALA4402543 | cell-free format | Scientific Literature |