#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4053085	Binding	Inhibition of ATP synthase in Mycobacterium smegmatis inverted membrane vesicles using NADH as substrate incubated for 60 mins by luciferin-luciferase reaction based bioluminescence assay	Mycolicibacterium smegmatis	33	ALA4052589	assay format	Scientific Literature
2.	ALA4053086	Functional	Antimycobacterial activity against Mycobacterium tuberculosis H37Rv by turbidometric method	Mycobacterium tuberculosis	35	ALA4052589	assay format	Scientific Literature
3.	ALA4053092	Functional	Antimycobacterial activity against Mycobacterium tuberculosis H37Rv harboring ATP synthase subunit-a K179N mutant supplemented with 4 fold MIC of 3-(4-Morpholinophenyl)-4-((pyridin-2-ylmethyl)amino)cyclobut-3-ene-1,2-dione	Mycobacterium tuberculosis	5	ALA4052589	assay format	Scientific Literature
4.	ALA4053093	Functional	Antimycobacterial activity against Mycobacterium tuberculosis H37Rv harboring ATP synthase subunit-c D28N mutant supplemented with 4 fold MIC of 3-(4-Morpholinophenyl)-4-((pyridin-2-ylmethyl)amino)cyclobut-3-ene-1,2-dione	Mycobacterium tuberculosis	5	ALA4052589	assay format	Scientific Literature
5.	ALA4053094	Functional	Antimycobacterial activity against Mycobacterium tuberculosis H37Rv harboring ATP synthase subunit-c D28N mutant supplemented with 8 fold MIC of 3-(4-Morpholinophenyl)-4-((pyridin-2-ylmethyl)amino)cyclobut-3-ene-1,2-dione	Mycobacterium tuberculosis	5	ALA4052589	assay format	Scientific Literature
6.	ALA4053095	Functional	Antimycobacterial activity against Mycobacterium tuberculosis H37Rv harboring ATP synthase subunit a K179N mutant supplemented with 8 fold MIC of 3-(4-Morpholinophenyl)-4-((pyridin-2-ylmethyl)amino)cyclobut-3-ene-1,2-dione	Mycobacterium tuberculosis	5	ALA4052589	assay format	Scientific Literature
7.	ALA4053098	Functional	Antimycobacterial activity against Mycobacterium tuberculosis H37Rv infected in BALB/c mouse assessed as bacterial growth inhibition at 100 to 200 mg/kg, po qd administered every 6 days for 2 weeks	Mycobacterium tuberculosis	1	ALA4052589	organism-based format	Scientific Literature
8.	ALA4053101	Functional	Induction of membrane damage in Mycobacterium bovis BCG after 60 mins by DiOC2 probe-based fluorescence assay	Mycobacterium tuberculosis	6	ALA4052589	assay format	Scientific Literature
9.	ALA4053102	Unassigned	Ratio of IC50 for induction of membrane damage in Mycobacterium bovis BCG to IC50 for ATP synthase in Mycobacterium smegmatis		6	ALA4052589	assay format	Scientific Literature
10.	ALA4053103	Functional	Selectivity ratio of MIC for Mycobacterium tuberculosis H37Rv harboring ATP synthase subunit-a K179N mutant supplemented with 4 fold MIC of 3-(4-Morpholinophenyl)-4-((pyridin-2-ylmethyl)amino)cyclobut-3-ene-1,2-dione to MIC for Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis	5	ALA4052589	assay format	Scientific Literature
11.	ALA4053104	Functional	Selectivity ratio of MIC for Mycobacterium tuberculosis H37Rv harboring ATP synthase subunit-c D28N mutant supplemented with 4 fold MIC of 3-(4-Morpholinophenyl)-4-((pyridin-2-ylmethyl)amino)cyclobut-3-ene-1,2-dione to MIC for Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis	5	ALA4052589	assay format	Scientific Literature
12.	ALA4053105	Functional	Selectivity ratio of MIC for Mycobacterium tuberculosis H37Rv harboring ATP synthase subunit-c D28N mutant supplemented with 8 fold MIC of 3-(4-Morpholinophenyl)-4-((pyridin-2-ylmethyl)amino)cyclobut-3-ene-1,2-dione to MIC for Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis	5	ALA4052589	assay format	Scientific Literature
13.	ALA4053106	Functional	Selectivity ratio of MIC for Mycobacterium tuberculosis H37Rv harboring ATP synthase subunit a K179N mutant supplemented with 8 fold MIC of 3-(4-Morpholinophenyl)-4-((pyridin-2-ylmethyl)amino)cyclobut-3-ene-1,2-dione to MIC for Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis	5	ALA4052589	assay format	Scientific Literature
14.	ALA4053108	ADME	Ratio of free plasma concentration in BALB/c mouse infected with Mycobacterium tuberculosis H37Rv in absence of pan CYP inhibitor ABT to presence of pan CYP inhibitor ABT	Mus musculus	1	ALA4052589	cell-free format	Scientific Literature
15.	ALA4053109	Unassigned	Time required for free plasma concentration to maintain above in vitro MIC for Mycobacterium tuberculosis H37Rv in BALB/c mouse infected with Mycobacterium tuberculosis H37Rv at 100 mg/kg, po in presence of pan CYP inhibitor ABT	Mus musculus	1	ALA4052589	organism-based format	Scientific Literature
16.	ALA4774531	Binding	Inhibition of ATP synthase in Mycobacterium tuberculosis H37Rv assessed as reduction in bacterial growth incubated for 7 days by microplate alamar blue assay	Mycobacterium tuberculosis H37Rv	46	ALA4765447	assay format	Scientific Literature
17.	ALA4774532	ADME	Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	Chlorocebus sabaeus	25	ALA4765447	cell-based format	Scientific Literature
18.	ALA4774533	Binding	Inhibition of ATP synthase in multi-drug resistant Mycobacterium tuberculosis clinical isolate 13946 assessed as reduction in bacterial growth incubated for 7 days by microplate alamar blue assay	Mycobacterium tuberculosis	8	ALA4765447	assay format	Scientific Literature
19.	ALA4774534	Binding	Inhibition of ATP synthase in multi-drug resistant Mycobacterium tuberculosis clinical isolate 14862 assessed as reduction in bacterial growth incubated for 7 days by microplate alamar blue assay	Mycobacterium tuberculosis	8	ALA4765447	assay format	Scientific Literature
20.	ALA4774535	ADME	Half life in CD-1 mouse hepatocytes at 1 uM measured after 30 mins by LC-MS/MS analysis	Mus musculus	7	ALA4765447	cell-based format	Scientific Literature